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NCT03930758: DIABETICBONE
Preventing Diabetic Osteoporosis With Exercise
NA trial testing Behavior intervention of uphill exercise in Diabetes Mellitus, Type 2 in 15 participants. Completed in 20 December 2012.
5 December 2012
Quick facts
| Lead sponsor | University of Michigan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | factorial |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 15 |
| Start date | 8 October 2009 |
| Primary completion | 5 December 2012 |
| Estimated completion | 20 December 2012 |
Drugs / interventions tested
- Behavior intervention of uphill exercise
- Dietary intervention of exercise before the meal
- Dietary intervention of uphill exercise
- Dietary intervention of exercise after the meal
- Behavior intervention of downhill exercise
- Dietary intervention of exercise before the meal
- Behavioral intervention of downhill exercise
- Dietary intervention of exercise after the meal
- Behavioral intervention of sedentary no-exercise trial
- Dietary intervention of eating two meals
Conditions studied
- Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
Sponsor
University of Michigan
Who can join
Adults 50 to 65, female only, with Diabetes Mellitus, Type 2. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The two specific aims of the study were to determine whether: 1. Greater mechanical loading of downhill exercise will increase the osteogenic index (ratio between CICP, the marker of bone formation (c-terminal propeptide of type I collagen, and CTX, the marker of bone resorption (c terminal telopeptide of type I collagen)) to a greater extent than uphill exercise that provides lower ground-reaction force; 2. Exercise after the meals will induce greater osteogenic response than exercise pefore the meals as it is known that meal eating during daytime inhibits bvone resorption markers.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Nutrient Intake Prior to Exercise Is Necessary for Increased Osteogenic Marker Response in Diabetic Postmenopausal Women.
Borer KT, Zheng Q, Jafari A, Javadi S, et al · · 2019 · cited 11× · PMID 31261978 · DOI 10.3390/nu11071494
Verify or expand the search:
- PubMed search for NCT03930758
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Michigan trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03930758 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Michigan
- Last refreshed: 29 April 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03930758.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing