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NCT03928782

Dose-effect Relationship Between microRNAs in Peripheral Blood and Radiation Injury

Status unknown Last updated 26 April 2019
What this trial tests

trial testing 5 Gy or 10 Gy units of whole-body radiation in Radiation Injuries, Experimental in 8 participants. Status unknown.

Timeline
1 December 2018
Primary endpoint
1 July 2019
1 September 2019

Quick facts

Lead sponsorAffiliated Hospital to Academy of Military Medical Sciences
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment8
Start date1 December 2018
Primary completion1 July 2019
Estimated completion1 September 2019
Sites2 locations across China

Drugs / interventions tested

Conditions studied

Sponsor

Affiliated Hospital to Academy of Military Medical Sciences

Who can join

Adults 18 to 50, any sex, with Radiation Injuries, Experimental. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Rapid and accurate assessment of radiation injury dose is the key to success in early treatment and an urgent issue to be solved in clinical medicine.Researches showed that the expression of the microRNAs in human peripheral blood had much correlation with radiation injury resulted from different dosages of radiation.In this study,acute leukemic patients who will be pretreated by whole-body radiation are taked as the object of study,and biochip technology are adopted to detect the expression levels of the microRNAs in subject peripheral blood before-and-after radiation,and different expression is tested and Bioinformatics prediction,to evaluate the correlation between radiation injury dose and expression levels of the microRNAs in human peripheral blood.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Trials by the same sponsor.

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Data sources for this page

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