Transforaminal Epidural Injection in Acute Sciatica (TEIAS)

NCT03924791 NA RECRUITING

Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery. However, patients may experience severe discomfort due to pain in the leg which can lead to decreased physical activity and socio-economic problems. An adequate therapy to alleviate symptoms during this period of 'wait-and-see' is lacking. In this study, patients will be randomized to treatment with transforaminal epidural injections or standard oral pain medication.

Details

Lead sponsor	C.L.A.Vleggeert-Lankamp
Phase	NA
Status	RECRUITING
Enrolment	142
Start date	2019-06-01
Completion	2026-07

Conditions

• Sciatica
• Sciatica Due to Intervertebral Disc Disorder
• Sciatic Radiculopathy

Interventions

• Lidocaine
• Methylprednisolone Acetate
• Dexamethasone

Primary outcomes

• Numerical Rating Scale (NRS) for leg pain — 2 weeks after randomization
  Pain intensity in the leg using the NRS. 0 is the minimal score indicating no pain, 10 is the maximum indicating the worst imaginable pain. Scale increases with increments of 1.

Countries

Netherlands