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NCT03918330
Spatial Analysis of the Intestinal Microbiota in Healthy Subjects
trial in Healthy Subjects in 10 participants. Completed in 10 October 2024.
28 February 2019
Quick facts
| Lead sponsor | Örebro University, Sweden |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 10 |
| Start date | 1 August 2018 |
| Primary completion | 28 February 2019 |
| Estimated completion | 10 October 2024 |
| Sites | 1 location across Sweden |
Conditions studied
- Healthy Subjects — all drugs for Healthy Subjects →
Sponsor
Örebro University, Sweden
Who can join
Adults 18 to 65, any sex, with Healthy Subjects. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Research on the human intestinal microbiota is common as there is rising evidence of its influence on host physiology and several diseases. Predominantly, it has been based on analyses of faecal samples because of their easy sampling. A minority of studies investigated the gut microbiota using mucosal samples. Not much is known about the spatial differences in microbiota composition along the large bowel. The spatial differences of the gut microbiota without preparation of the bowel have not been analysed yet. Furthermore, the composition of the microbiota of the luminal gut content has not been analysed yet. This study aims to gain knowledge of the microbial composition of luminal and mucosal samples at different segments of the lower gastrointestinal tract: ileum, caecum, ascending colon, transverse colon, descending colon, sigmoid colon and rectum, as well as of rectal swabs and faecal samples.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Fecal samples and rectal swabs adequately reflect the human colonic luminal microbiota.
Rode J, Brengesjö Johnson L, König J, Rangel I, et al · · 2024 · cited 6× · PMID 39439236 · DOI 10.1080/19490976.2024.2416912
Verify or expand the search:
- PubMed search for NCT03918330
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Örebro University, Sweden trials
Trials by the same sponsor.
- NCT07521709 — Evaluation of an Online ACT and Compassion-based Intervention for Disorders of Gut-Brain Interaction · NA · not yet recruiting
- NCT07350239 — Clinical, Microbial and Tissue-based Characterization of Patients Treated for Severe Temporomandibular Joint Pathology · not yet recruiting
- NCT07527793 — Monitoring Changes in Blood Circulating Metabolites Using Minimally Invasive Techniques · NA · recruiting
- NCT07175402 — Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction - Beta Trial · NA · completed
- NCT06887751 — Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03918330 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Örebro University, Sweden
- Last refreshed: 27 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03918330.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing