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NCT03918161

Magnetic Resonance Elastography of Transplanted Kidney (GREFFE_ELASTO IRM)

Completed NA Last updated 26 March 2021
What this trial tests

NA trial testing MRE exam in Interstitial Fibrosis/Tubular Atrophy of Transplanted Kidneys in 73 participants. Completed in 12 December 2020.

Timeline
24 July 2019
Primary endpoint
10 December 2020
12 December 2020

Quick facts

Lead sponsorUniversity Hospital, Bordeaux
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment73
Start date24 July 2019
Primary completion10 December 2020
Estimated completion12 December 2020
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Bordeaux

Who can join

Adults 18 to 65, any sex, with Interstitial Fibrosis/Tubular Atrophy of Transplanted Kidneys. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

: GREFFE\_ELASTO IRM will evaluate Magnetic Resonance Elastography (MRE) in renal transplant patients with suspected interstitial fibrosis/tubular atrophy lesions requiring biopsy graft sampling under ultrasound control. The main objective is to search a correlation between renal graft parenchymal elasticity values obtained in vivo by MRE, and the histological data of renal fibrosis by biopsy sampling, and providing a non-invasive tool capable of detecting and monitoring this development over time, making possible in the future to reduce the number of renal biopsies.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Magnetic Resonance Elastography as Surrogate Marker of Interstitial Fibrosis in Kidney Transplantation: A Prospective Study.
    Chauveau B, Merville P, Soulabaille B, Taton B, et al · · 2022 · cited 10× · PMID 36514413 · DOI 10.34067/kid.0004282022

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Trials by the same sponsor.

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Data sources for this page

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