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NCT03917368: US-JVP
Ultrasound Evaluation of the Jugular Venous Pulse (US-JVP)
NA trial testing Ultrasound scan of the internal jugular veins in Emergencies in 300 participants. Status unknown.
31 October 2019
Quick facts
| Lead sponsor | S. Anna Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 300 |
| Start date | 16 September 2016 |
| Primary completion | 31 October 2019 |
| Estimated completion | 31 May 2020 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Ultrasound scan of the internal jugular veins
Conditions studied
- Emergencies — all drugs for Emergencies →
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
- Neurovascular Disorders — all drugs for Neurovascular Disorders →
Sponsor
S. Anna Hospital
Who can join
18 and older, any sex, with Emergencies or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The jugular venous pulse (JVP) reflects changes in the right atrial pressure and its evaluation can be useful in managing many emergency conditions for guiding the fluid administration as well as in the diagnosis and/or prognosis of many heart and lung diseases. The present study aims: i) To validate a novel ultrasonographic (US) technique for obtaining the JVP from a high-resolution B-mode sonograms sequence, recording the changes of the cross-sectional area (CSA) of the internal jugular veins (IJV) over the cardiac cycle; ii) To develop physical and mathematical models capable of providing an indirect estimate of central venous pressure (CVP) from the changes in IJV-CSA acquired through the US investigation, and iii) To test the transferability of the novel US-JVP technique in a clinical setting.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Central venous pressure estimation from ultrasound assessment of the jugular venous pulse.
Zamboni P, Malagoni AM, Menegatti E, Ragazzi R, et al · · 2020 · cited 17× · PMID 33112871 · DOI 10.1371/journal.pone.0240057
Verify or expand the search:
- PubMed search for NCT03917368
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03917368 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by S. Anna Hospital
- Last refreshed: 17 April 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03917368.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing