Last reviewed · How we verify
NCT03916809
EMST in Patients Undergoing CRT for HNCA
NA trial testing EMST in Head and Neck Neoplasms in 30 participants. Currently enrolling.
1 August 2025
Quick facts
| Lead sponsor | University of Wisconsin, Milwaukee |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | supportive care |
| Enrollment | 30 |
| Start date | 12 July 2017 |
| Primary completion | 1 August 2025 |
| Estimated completion | 1 August 2025 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- EMST
Conditions studied
- Head and Neck Neoplasms — all drugs for Head and Neck Neoplasms →
- Deglutition Disorders — all drugs for Deglutition Disorders →
Sponsor
University of Wisconsin, Milwaukee
Who can join
18 and older, any sex, with Head and Neck Neoplasms or Deglutition Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a randomized trial examining the impact of expiratory muscle strength training (EMST) on maintenance of safe and efficient oropharyngeal swallow function in persons with cancer of the head and neck (HNCA) undergoing treatment with radiation therapy or chemoradiotherapy (RT/CRT).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Management of dysphagia in head and neck cancer: current and future perspectives.
Schellen C, Konings M, Vergauwen A, Van den Steen L, et al · · 2026 · PMID 41939474 · DOI 10.3389/fonc.2026.1799956
Verify or expand the search:
- PubMed search for NCT03916809
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of EMST
Trials testing the same drug.
- NCT07371351 — "Effects of EMST and Triflo on Voice Parameters and Vocal Fatigue" · NA · not yet recruiting
- NCT03696576 — Expiratory Muscle Strength Training and Phonation Resistance Training Exercises For Elderly Patients With Vocal Fold Atr · NA · terminated
Other recruiting trials for Head and Neck Neoplasms
Currently open trials in the same condition.
- NCT07491536 — Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis · NA · recruiting
- NCT06912087 — Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC · Phase 1 · recruiting
- NCT06998069 — Head and Neck Cancer Study Project in the Geriatric Population · Phase 3 · recruiting
- NCT07158164 — DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment · Phase 4 · recruiting
- NCT06303180 — NIDCD Otolaryngology Clinical Protocol Biospecimen Bank · recruiting
Other University of Wisconsin, Milwaukee trials
Trials by the same sponsor.
- NCT05736302 — Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled Water · recruiting
- NCT06054386 — Attention Bias Modification Training for Social Phobia (ABMSP) · NA · recruiting
- NCT05330780 — Breathing Room Intervention to Achieve Better Lung Health in Older Adults · NA · completed
- NCT05112562 — Attentional Bias Modification Training for E-cigarette Users · NA · unknown
- NCT04660708 — Manual Physical Therapy During Pregnancy on Post Partum Perineal Trauma and Pain · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03916809 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Wisconsin, Milwaukee
- Last refreshed: 4 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03916809.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing