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NCT03906890

Chromium Contamination of Parenteral Nutrition

Completed Last updated 4 June 2020
What this trial tests

trial in Trace Element Excess in 75 participants. Completed in 30 September 2019.

Timeline
25 February 2018
Primary endpoint
30 September 2019
30 September 2019

Quick facts

Lead sponsorThe Hospital for Sick Children
StatusCompleted
Study typeOBSERVATIONAL
Enrollment75
Start date25 February 2018
Primary completion30 September 2019
Estimated completion30 September 2019
Sites1 location across Canada

Conditions studied

Sponsor

The Hospital for Sick Children

Who can join

Under 18, any sex, with Trace Element Excess. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It has been observed that patients on total parenteral nutrition (TPN) have high plasma chromium level. There is reason to believe that TPN solutions contain chromium and possibly other trace elements as contaminants. Chromium in particular can lead to kidney damage. The purpose of this research are 1). to collect discarded TPN samples from patients on TPN for analysis and compare analyzed concnetrations of trace elements to prescribed concentrations. 2\) analyze small volume parenterals obtained from a TPN supplier for evaluation of trace elements contcentrations to be compared with what is reported on the label. 3\) retrospectively collect blood levels of chromium from charts of patients on home TPN who consented to have their TPN samples analyzed (#1 above), as well as prescribed Cr in their TPN at the time blood levels are recorded.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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