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NCT03904134: BMT CTN 1702
Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702)
NA trial testing Donor Search Prognosis Score in Acute Myeloid Leukemia in 1,753 participants. Completed in 6 January 2025.
6 January 2025
Quick facts
| Lead sponsor | Center for International Blood and Marrow Transplant Research |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 1,753 |
| Start date | 14 June 2019 |
| Primary completion | 6 January 2025 |
| Estimated completion | 6 January 2025 |
| Sites | 52 locations across United States |
Drugs / interventions tested
- Donor Search Prognosis Score
Conditions studied
- Acute Myeloid Leukemia — all drugs for Acute Myeloid Leukemia →
- Acute Lymphoblastic Leukemia — all drugs for Acute Lymphoblastic Leukemia →
- Myelodysplastic Syndromes — all drugs for Myelodysplastic Syndromes →
- Non-hodgkin Lymphoma — all drugs for Non-hodgkin Lymphoma →
Sponsor
Center for International Blood and Marrow Transplant Research — full company profile →
Who can join
Eligibility, any sex, with Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine if a search strategy of searching for an HLA-matched unrelated donor for allogeneic transplantation if possible then an alternative donor if an HLA-matched unrelated donor is not available versus proceeding directly to an alternative donor transplant will result in better survival for allogeneic transplant recipients within 2 years after study enrollment.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Improved GRFS after posttransplant cyclophosphamide-based vs ATG-based HLA-mismatched unrelated donor transplant.
Jimenez Jimenez A, Komanduri K, Brown S, Wang T, et al · · 2022 · cited 24× · PMID 35793451 · DOI 10.1182/bloodadvances.2022007596 -
Hematology 2022-what is complete HLA match in 2022?
Spellman SR. · · 2022 · cited 22× · PMID 36485162 · DOI 10.1182/hematology.2022000326 -
Access to Allogeneic Cell Transplantation Based on Donor Search Prognosis: BMT CTN 1702 Trial.
Dehn JG, Logan B, Lee SJ, Shaw BE, et al · · 2026 · cited 3× · PMID 41213499 · DOI 10.1016/j.jtct.2025.11.010
Verify or expand the search:
- PubMed search for NCT03904134
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Acute Myeloid Leukemia
Currently open trials in the same condition.
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- NCT06782542 — Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for I · Phase 2 · recruiting
- NCT07177079 — High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML · Phase 1 · recruiting
- NCT07384715 — First-in-human (FIH) Trial of GEN3018 in Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) or Higher-risk Myelod · Phase 1 · recruiting
- NCT07107126 — Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes · Phase 1 · recruiting
Other Center for International Blood and Marrow Transplant Research trials
Trials by the same sponsor.
- NCT06001385 — HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cycloph · Phase 2 · active not recruiting
- NCT05224661 — Molecular Evaluation of AML Patients After Stem Cell Transplant to Understand Relapse Events · active not recruiting
- NCT03992352 — Composite Health Assessment Risk Model (CHARM) for Older Adults (BMT CTN 1704) · completed
- NCT03718546 — Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors · completed
- NCT03619551 — Conditioning SCID Infants Diagnosed Early · Phase 2 · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03904134 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Center for International Blood and Marrow Transplant Research
- Last refreshed: 5 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03904134.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing