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NCT03902912
Effect of Prednisolone Treatment on Uterine Natural Killer Cells
Phase 3 trial testing Prednisolone in Recurrent Miscarriage in 84 participants. Currently enrolling.
30 April 2027
Quick facts
| Lead sponsor | Chinese University of Hong Kong |
|---|---|
| Phase | Phase 3 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 84 |
| Start date | 30 July 2019 |
| Primary completion | 30 April 2027 |
| Estimated completion | 30 April 2028 |
| Sites | 1 location across Hong Kong |
Drugs / interventions tested
- Prednisolone — full drug profile →
Conditions studied
- Recurrent Miscarriage — all drugs for Recurrent Miscarriage →
Sponsor
Chinese University of Hong Kong
Who can join
Adults 18 to 40, female only, with Recurrent Miscarriage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate the role of uNK cells and the association with prednisolone.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure.
Guan D, Chen Z, Zhang Y, Sun W, et al · · 2025 · cited 7× · PMID 40325291 · DOI 10.1111/cpr.70037
Verify or expand the search:
- PubMed search for NCT03902912
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other recruiting trials for Recurrent Miscarriage
Currently open trials in the same condition.
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Other Chinese University of Hong Kong trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03902912 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
- Last refreshed: 21 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03902912.
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