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NCT03898310
UTI Prophylaxis With Cranberry Extract After Female Incontinence Surgery
NA trial testing Cranberry extract capsules in Urinary Tract Infections in 141 participants. Completed in 22 January 2023.
22 January 2023
Quick facts
| Lead sponsor | University of Oklahoma |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 141 |
| Start date | 5 February 2019 |
| Primary completion | 22 January 2023 |
| Estimated completion | 22 January 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cranberry extract capsules
- Placebo capsule
Conditions studied
- Urinary Tract Infections — all drugs for Urinary Tract Infections →
- Incontinence — all drugs for Incontinence →
Sponsor
University of Oklahoma
Who can join
Adults 18 to 80, female only, with Urinary Tract Infections or Incontinence. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The risk of urinary tract infection (UTI) following female incontinence surgery ranges between 6-48%. The literature has shown mixed results of the therapeutic efficacy of cranberry extract to prevent UTI in females, with some promising preliminary work in the prevention of UTI's following gynecologic surgery. The researchers will conduct a study of the effect of cranberry extracts on preventing urinary tract infections following mid urethral slings, which are the most common urinary incontinence procedures.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Prophylactic antibiotics for preventing infection after continence surgery in women with stress urinary incontinence.
Temtanakitpaisan T, Buppasiri P, Lumbiganon P, Laopaiboon M, et al · · 2022 · cited 1× · PMID 35349162 · DOI 10.1002/14651858.cd012457.pub2
Verify or expand the search:
- PubMed search for NCT03898310
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cranberry extract capsules
Trials testing the same drug.
- NCT05931237 — Cranberry Flavan-3-ols Consumption and Gut Microbiota in Healthy Adults · NA · completed
Other recruiting trials for Urinary Tract Infections
Currently open trials in the same condition.
- NCT06976125 — Application of a Prediction Model for Directing Antibiotic Use in the Treatment of Urinary Tract Infection in an Ambulat · NA · recruiting
- NCT06808451 — Diagnosis and Treatment of Urinary Tract Infection Using DNA Polymerase Chain Reaction Versus Urine Culture · NA · recruiting
- NCT07186465 — Microbiome-Modulating Prophylaxis RCT: Antibiotic vs Gynoflor in Postmenopausal Women With Recurrent Cystitis · Phase 4 · recruiting
- NCT07207291 — Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers · Phase 1 · recruiting
- NCT06715306 — Intravenous Versus Oral Treatment of the Main Acute Infections · NA · recruiting
Other University of Oklahoma trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03898310 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Oklahoma
- Last refreshed: 13 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03898310.
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