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NCT03896906
Preoxygenation With a High-flow Nasal Cannula or a Simple Mask Before General Anesthesia in Head and Neck Surgery
NA trial testing High-flow nasal cannula in Head and Neck Neoplasm in 52 participants. Completed in 7 April 2020.
7 April 2020
Quick facts
| Lead sponsor | Asan Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 52 |
| Start date | 8 May 2019 |
| Primary completion | 7 April 2020 |
| Estimated completion | 7 April 2020 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- High-flow nasal cannula
- simple mask
Conditions studied
- Head and Neck Neoplasm — all drugs for Head and Neck Neoplasm →
Sponsor
Asan Medical Center
Who can join
Adults 19 to 80, any sex, with Head and Neck Neoplasm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Objectives: To assess arterial oxygen partial pressure (PaO2) at defined time points during the preoxygenation and to compare between high flow heated humidified nasal oxygen versus standard preoxygenation with oxygen insufflation via face mask over at least 5 minutes Methods: This randomized, single-blinded, prospective study was conducted at Asan Medical Center in Seoul, Republic of Korea. Populations: Patients undergoing head and neck surgery Expected outcomes: The course of PaO2 levels is superior to those of the face mask during the whole preoxygenation procedure and after the intubation.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Comparison of preoxygenation with a high-flow nasal cannula and a simple mask before intubation during induction of general anesthesia in patients undergoing head and neck surgery: Study protocol clinical trial (SPIRIT Compliant).
Jo JY, Kim WJ, Ku S, Choi SS. · · 2020 · cited 5× · PMID 32195955 · DOI 10.1097/md.0000000000019525 -
Comparison of preoxygenation with a high-flow nasal cannula and a simple face mask before intubation in Korean patients with head and neck cancer.
Jo JY, Yoon J, Jang H, Kim WJ, et al · · 2024 · PMID 38303582 · DOI 10.4266/acc.2022.01543
Verify or expand the search:
- PubMed search for NCT03896906
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High-flow nasal cannula
Trials testing the same drug.
- NCT07155330 — High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients · NA · completed
- NCT06663293 — Comparison of High Flow vs Standard Nasal Cannula in Children With Burns Under Sedoanalgesia · NA · completed
- NCT05012696 — Physiological Effects of Non-invasive Mechanical Ventilation Versus High-flow Nasal Cannula in Critically Ill Patients a · NA · completed
- NCT04507425 — High Flow Nasal Cannula With Noninvasive Ventilation · NA · completed
- NCT04471220 — Exercise Capacity Under Various FiO2 and Oxygen Flow Rates Using HFNC · NA · completed
Other recruiting trials for Head and Neck Neoplasm
Currently open trials in the same condition.
- NCT04099290 — Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma · recruiting
- NCT06356272 — Oropharynx (OPX) Biomarker Trial · recruiting
- NCT04005521 — Randomized Study Regarding Preventive Jaw- and Swallowing Intervention for Patients With Head and Neck Cancer · NA · active not recruiting
- NCT03840421 — GP Vs PF As Induction Chemotherapy Combined with CCRT for Locoregionally Advanced Nasopharyngeal Carcinoma · Phase 3 · active not recruiting
Other Asan Medical Center trials
Trials by the same sponsor.
- NCT07530393 — Blood Viscosity and Outcomes After Elective Craniotomy · not yet recruiting
- NCT07010497 — A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Be · Phase 2 · recruiting
- NCT07382505 — Prospective Cohort Study of Minimal Residual Disease(MRD) Testing for Early Recurrence Detection in Endometrial and Cerv · not yet recruiting
- NCT07489092 — Feasibility of a Digital Rehabilitation Platform in Patients After ICU Discharge · NA · recruiting
- NCT07431762 — Comparison of Anti-Thrombotic Treatments Between Aspirin and Warfarin During Initial Six Months After Bioprpsthetic Hear · Phase 4 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03896906 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Asan Medical Center
- Last refreshed: 7 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03896906.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing