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NCT03896698: TUS
Feasibility Study of Transcranial Ultrasound Stimulation on Alzheimer's Disease Patients
NA trial testing Transcranial Ultrasound Stimulation in Alzheimer Disease in 10 participants. Status unknown.
31 May 2021
Quick facts
| Lead sponsor | National Yang Ming Chiao Tung University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | device feasibility |
| Enrollment | 10 |
| Start date | 23 August 2019 |
| Primary completion | 31 May 2021 |
| Estimated completion | 30 June 2021 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- Transcranial Ultrasound Stimulation
Conditions studied
- Alzheimer Disease — all drugs for Alzheimer Disease →
Sponsor
National Yang Ming Chiao Tung University
Who can join
Adults 55 to 90, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Currently, the main treatment method for Alzheimer's disease (AD) is chemotherapy. However, the effectiveness of drugs is moderate and there are several side effects. In this clinical trial, the investigators would like to activate the brain by the transcranial ultrasound stimulation (TUS). This is a feasibility study to evaluate the safety and initial effectiveness of TUS for the treatment of patients with mild AD.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Current state of clinical ultrasound neuromodulation.
Matt E, Radjenovic S, Mitterwallner M, Beisteiner R. · · 2024 · cited 27× · PMID 38962179 · DOI 10.3389/fnins.2024.1420255 -
Volume Changes in Brain Subfields of Patients with Alzheimer's Disease After Transcranial Ultrasound Stimulation.
Huang SY, Wu MT, Sun CF, Yang FY. · · 2025 · cited 1× · PMID 39941289 · DOI 10.3390/diagnostics15030359
Verify or expand the search:
- PubMed search for NCT03896698
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03896698 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Yang Ming Chiao Tung University
- Last refreshed: 28 April 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03896698.
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