NCT03892291: reTURN

Objective Dual-task Turning Measures for Return-to-duty Assessments

Completed Last updated 6 June 2025

What this trial tests

trial in Mild Traumatic Brain Injury in 185 participants. Completed in 1 September 2024.

Timeline

1 September 2018

Primary endpoint
1 September 2024

1 September 2024

Quick facts

Lead sponsor	Oregon Health and Science University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	185
Start date	1 September 2018
Primary completion	1 September 2024
Estimated completion	1 September 2024
Sites	6 locations across United States

Conditions studied

• Mild Traumatic Brain Injury — all drugs for Mild Traumatic Brain Injury →
• Gait — all drugs for Gait →
• Balance — all drugs for Balance →
• Veterans — all drugs for Veterans →

Sponsor

Oregon Health and Science University

Who can join

Adults 18 to 50, any sex, with Mild Traumatic Brain Injury or Gait. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall objective is to evaluate objective dual-task turning measures for use as rehabilitative outcomes and as tools for return-to-duty assessments in individuals with mild traumatic brain injury (mTBI).This project consists of three goals examining the I) Diagnostic Accuracy, II) Predictive Capacity, and III) Responsiveness to Intervention of dual task turning measures in individuals with mTBI.

The investigators hypothesize that objective measures of dual-task turning will have high diagnostic accuracy, predictive capacity, and responsiveness to intervention in people with mTBI.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. Objective Dual-Task Turning Measures for Return-to-Duty Assessment After Mild Traumatic Brain Injury: The ReTURN Study Protocol.
   Fino PC, Weightman MM, Dibble LE, Lester ME, et al · · 2020 · cited 11× · PMID 33519659 · DOI 10.3389/fneur.2020.544812
2. Relation Between Cognitive Assessment and Clinical Physical Performance Measures After Mild Traumatic Brain Injury.
   Antonellis P, Weightman MM, Fino PC, Chen S, et al · · 2024 · cited 7× · PMID 37931890 · DOI 10.1016/j.apmr.2023.10.013
3. Reconsidering Vestibular/Ocular Motor Screening Cutoff Scores for Concussion.
   Weightman MM, King LA, Fino PC, Dibble LE, et al · · 2024 · cited 5× · PMID 37856171 · DOI 10.1093/milmed/usad394
4. A Hybrid Assessment of Clinical Mobility Test Items for Evaluating Individuals With Mild Traumatic Brain Injury.
   Fino PC, Michielutti PG, Pelo R, Parrington L, et al · · 2023 · cited 5× · PMID 36538333 · DOI 10.1097/npt.0000000000000427
5. Between-site equivalence of turning speed assessments using inertial measurement units.
   Parrington L, King LA, Weightman MM, Hoppes CW, et al · · 2021 · cited 5× · PMID 34530311 · DOI 10.1016/j.gaitpost.2021.09.164
6. Exploring Vestibular Ocular Motor Screening in Adults With Persistent Complaints After Mild Traumatic Brain Injury.
   Parrington L, King LA, Hoppes CW, Klaiman MJ, et al · · 2022 · cited 3× · PMID 35067602 · DOI 10.1097/htr.0000000000000762
7. Objective Turning Measures Improve Diagnostic Accuracy and Relate to Simulated Real-World Mobility/Combat Readiness in Chronic Mild Traumatic Brain Injury.
   Fino PC, Antonellis P, Parrington L, Weightman MM, et al · · 2025 · cited 1× · PMID 40135290 · DOI 10.1089/neu.2024.0127
8. Gait during community ambulation and laboratory-based walking in people with mild traumatic brain injury.
   Antonellis P, Lee JW, Fino PC, Weightman MM, et al · · 2025 · cited 1× · PMID 39813789 · DOI 10.1016/j.gaitpost.2025.01.002