Who is sponsoring NCT03891212?

NCT03891212 is sponsored by Xiangya Hospital of Central South University.

What drugs are being tested in NCT03891212?

Interventions in NCT03891212: Placed in prone position for at least 16 consecutive hours a day..

What condition does NCT03891212 study?

NCT03891212 studies Severe Pneumonia.

Is NCT03891212 still recruiting?

NCT03891212 is currently status unknown. Last updated 26 March 2019.

Last reviewed 2019-03-26 · How we verify

NCT03891212

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Prone Position Drainage on the Efficacy of Severe Pneumonia，a Multicenter Randomized Controlled Trial

Status unknown NA Last updated 26 March 2019

What this trial tests

NA trial testing Placed in prone position for at least 16 consecutive hours a day. in Severe Pneumonia in 500 participants. Status unknown.

Timeline

1 April 2019

Primary endpoint
1 April 2021

1 April 2022

Quick facts

Lead sponsor	Xiangya Hospital of Central South University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	500
Start date	1 April 2019
Primary completion	1 April 2021
Estimated completion	1 April 2022
Sites	1 location across China

Drugs / interventions tested

Placed in prone position for at least 16 consecutive hours a day.

Conditions studied

Severe Pneumonia — all drugs for Severe Pneumonia →

Sponsor

Xiangya Hospital of Central South University

Who can join

Adults 18 to 75, any sex, with Severe Pneumonia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Enrollment criteria and clinical data collection: follow the principles of medical ethics, the development of inclusion and exclusion criteria, Select all eligible patients with severe pneumonia(SP) who were admitted to the hospital during the study date.The diagnostic criteria we will use for SP are based on the Infectious Diseases Society of America/American Thoracic Society guidelines.Primary outcome measures：a.CURB-65 Score for Pneumonia Severity;b.The changes in inflammation and coagulation indicators: C-reactive protein, procalcitonin, and d-dimer;c.Chest x-ray changes;d.Mortality rate after 28 days;e.The time of mechanical ventilation, total duration of ICU stay, hospitalization, and antibiotic use;f.The time of bacterial cultures becoming negative;g.Daily sputum drainage.The aim of this study is to evaluate the anti-infective effectiveness and safety of prone position drainage compared with supine position on SP treatment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Prone position for acute respiratory failure in adults.
Bloomfield R, Noble DW, Sudlow A. · · 2015 · cited 93× · PMID 26561745 · DOI 10.1002/14651858.cd008095.pub2

Verify or expand the search:

Other recruiting trials for Severe Pneumonia

Currently open trials in the same condition.

NCT07461714 — AI-Driven Accurate Diagnosis of Pathogens in Severe Pneumonia · active not recruiting
NCT06538441 — Dynamic Pattern of Etiology, Immunoinflammatory Factors and Their Association With Prognosis of Severe Pneumonia · active not recruiting
NCT06514781 — The Application of Different Sedation Protocols in ICU Patients With Severe Pneumonia · recruiting
NCT06114784 — Microbiome and Host Susceptibility in Severe Pneumonia, a Prospective, Multicenter, Cohort Study · recruiting
NCT06516601 — Fulminant Severe CAP - an Observational Study · recruiting

Other Xiangya Hospital of Central South University trials

Trials by the same sponsor.

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NCT07412223 — Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery · Phase 4 · not yet recruiting
NCT07369960 — Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Glo · NA · recruiting
NCT07369999 — Effects of Butylphthalide Enhanced With Tenecteplase on Neurological Function in Mild Disabling Acute Ischemic Stroke · Phase 3 · not yet recruiting
NCT07309913 — China Atrial Fibrillation With Complex Metabolic Disorder Cohort Study (CAME Cohort) · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03891212 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Xiangya Hospital of Central South University
Last refreshed: 26 March 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03891212.

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