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NCT03890016: LAT

Study Comparing Modified Lee White Clotting Time Against Twenty Minute Whole Blood Clotting Test in Snakebite Victims

Completed Last updated 17 August 2020
What this trial tests

trial testing 20'Whole Blood ClottingTest (WBCT) in Coagulation Defect in 230 participants. Completed in 30 June 2020.

Timeline
1 May 2019
Primary endpoint
31 May 2020
30 June 2020

Quick facts

Lead sponsorAppu Suseel
StatusCompleted
Study typeOBSERVATIONAL
Enrollment230
Start date1 May 2019
Primary completion31 May 2020
Estimated completion30 June 2020
Sites1 location across India

Drugs / interventions tested

Conditions studied

Sponsor

Appu Suseel

Who can join

Eligibility, any sex, with Coagulation Defect or Snake Bites. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

20 minute Whole Blood Clotting Test(20'WBCT) recommended by World Health Organisation guidelines is probably the most routinely employed bed side screening tool in the country. The Modified Lee and White (MLW) method gives a value which when performed serially gives a trend in clotting time which the investigators hypothesise to be a better tool in serially assessing the victim compared to the 20'WBCT. The investigators propose that delayed reading of both MLW and 20'WBCT to check for clot stability at 30 minutes also provides added information in management of snake bite victims.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Comparing modified Lee and White method against 20-minute whole blood clotting test as bedside coagulation screening test in snake envenomation victims.
    Suseel A, Abraham SV, Paul S, Tomy MML, et al · · 2023 · cited 4× · PMID 37342654 · DOI 10.1590/1678-9199-jvatitd-2022-0088

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