Last reviewed · How we verify
NCT03889483
Neurophysiological Measurements Using the NeuroCatch™ Platform in Pediatric Concussion
NA trial testing NeuroCatch™ Platform in Children, Only in 105 participants. Status unknown.
30 September 2021
Quick facts
| Lead sponsor | Dr. Michael Esser |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 105 |
| Start date | 30 November 2018 |
| Primary completion | 30 September 2021 |
| Estimated completion | 30 December 2021 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- NeuroCatch™ Platform
Conditions studied
- Children, Only — all drugs for Children, Only →
- Traumatic Brain Injury — all drugs for Traumatic Brain Injury →
- Concussion, Mild — all drugs for Concussion, Mild →
- Pediatric ALL — all drugs for Pediatric ALL →
Sponsor
Dr. Michael Esser
Who can join
Adults 8 to 18, any sex, with Children, Only or Traumatic Brain Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
EEG signals have been collected and studied since the early 1990's as a way of assessing brain function at a gross level. As early as the 1930's a derivative of the raw EEG signal - event-related potentials (ERPs) - have been computed. The current research is primarily focused on three ERP components: the N100, P300 and N400. Each of the three ERPs have been studied in the academic laboratory for multiple decades. Through this research, a strong understanding has been developed regarding what can affect these components (e.g. task set, emotional state, etc.). However, these signals within various pediatric populations (e.g., those with persistent mTBI symptoms or multiple concussions) are not well characterized. Being able to safely and effectively employ the NeuroCatch™ Platform in a post-concussive pediatric cohort could provide researchers with the potential to elucidate the persistence of objective measures of impairment, patterns of recovery, and chronicity of problems due to mTBI in children. Secondly, understanding the degree to which these neurophysiological components fluctuate over time is crucial to the understanding of brain functioning. However, for this type of technology to be useful in quantifying brain health in this population,the degree to which a post-concussive pediatric brain naturally fluctuates in its processing capability must be quantified. NeuroCatch™ Platform has the ability to measure changes in several domains of brain function. These cognitive processes are foundational blocks for some of the highest cognitive processes: information integration and executive functioning.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03889483
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of NeuroCatch™ Platform
Trials testing the same drug.
- NCT03835962 — Development of a Reference Interval Database With the NeuroCatch™ Platform · NA · completed
Other recruiting trials for Children, Only
Currently open trials in the same condition.
- NCT07342751 — The Effect of Listening to Music During Mobilization on Pain and Fear in Children Undergoing Abdominal Surgery · NA · active not recruiting
- NCT07244068 — Effect of Mat Pilates on Pain and Postural Alignment in School Going Children With Upper Crossed Syndrome. · NA · recruiting
- NCT07428850 — Effect of Aerobic Exercises Versus Low Interval Training on Cardiorespiratory Fitness in School Going Chlidren. · NA · recruiting
- NCT06777875 — COMT and OPRM1 Polymorphisms and Their Effect on Post-Operative Pain in Children · recruiting
- NCT06505447 — PICU-related Sleep and Circadian Dysregulation Pilot Study · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03889483 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Michael Esser
- Last refreshed: 13 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03889483.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing