Last reviewed · How we verify
NCT03888456
Effects of OMT on ANS: a Thermography Study
NA trial testing osteopathic treatment in Autonomic Nervous System Imbalance in 40 participants. Completed in 23 July 2019.
30 June 2019
Quick facts
| Lead sponsor | Come Collaboration |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 40 |
| Start date | 26 March 2019 |
| Primary completion | 30 June 2019 |
| Estimated completion | 23 July 2019 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- osteopathic treatment
- sham
Conditions studied
- Autonomic Nervous System Imbalance — all drugs for Autonomic Nervous System Imbalance →
- Healthy — all drugs for Healthy →
Sponsor
Come Collaboration
Who can join
Adults 18 to 35, any sex, with Autonomic Nervous System Imbalance or Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
the study will investigate the effect of a specific type of touch intervention on the activity of autonomic nervous system measured using thermography
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Does Osteopathic Manipulative Treatment Induce Autonomic Changes in Healthy Participants? A Thermal Imaging Study.
Cerritelli F, Cardone D, Pirino A, Merla A, et al · · 2020 · cited 35× · PMID 33013294 · DOI 10.3389/fnins.2020.00887 -
Autonomic correlates of osteopathic manipulative treatment on facial functional mapping: an innovative approach based on thermal imaging.
Cerritelli F, Perpetuini D, Keys J, Merla A, et al · · 2025 · PMID 40025233 · DOI 10.1038/s41598-025-92092-8
Verify or expand the search:
- PubMed search for NCT03888456
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of osteopathic treatment
Trials testing the same drug.
- NCT07486011 — Effects of Osteopathic Treatment in Patients With Somatosensory Tinnitus · NA · completed
- NCT04999254 — Osteopathic Consultation in the Emergency Department for Fresh Lateral Ligament Sprain · NA · completed
- NCT04277039 — Effects of Osteopathic Treatment With Cognitive Training on Low Back Pain · NA · unknown
Other recruiting trials for Autonomic Nervous System Imbalance
Currently open trials in the same condition.
- NCT06359808 — Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis · recruiting
- NCT05212129 — Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome · NA · recruiting
Other Come Collaboration trials
Trials by the same sponsor.
- NCT04682002 — Low-back Pain During Pregnancy and Its Psycho-social Implications · NA · unknown
- NCT04277039 — Effects of Osteopathic Treatment With Cognitive Training on Low Back Pain · NA · unknown
- NCT03833635 — Effects of OMT on Premature Physiological Parameters · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03888456 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Come Collaboration
- Last refreshed: 24 July 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03888456.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing