NCT03887819 is a clinical trial of Hystological evaluation in Pulmonary Embolism, sponsored by University of Campania Luigi Vanvitelli.

Who is sponsoring NCT03887819?

NCT03887819 is sponsored by University of Campania Luigi Vanvitelli.

What drugs are being tested in NCT03887819?

Interventions in NCT03887819: Hystological evaluation.

What condition does NCT03887819 study?

NCT03887819 studies Pulmonary Embolism.

Is NCT03887819 still recruiting?

NCT03887819 is currently completed. Last updated 26 March 2019.

Last reviewed 2019-03-26 · How we verify

NCT03887819

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pulmonary Embolism: an Autopsy Study

Completed Last updated 26 March 2019

What this trial tests

trial testing Hystological evaluation in Pulmonary Embolism in 15 participants. Completed in 1 January 2019.

Timeline

1 January 2015

Primary endpoint
1 June 2018

1 January 2019

Quick facts

Lead sponsor	University of Campania Luigi Vanvitelli
Status	Completed
Study type	OBSERVATIONAL
Enrollment	15
Start date	1 January 2015
Primary completion	1 June 2018
Estimated completion	1 January 2019

Drugs / interventions tested

Hystological evaluation

Conditions studied

Pulmonary Embolism — all drugs for Pulmonary Embolism →

Sponsor

University of Campania Luigi Vanvitelli

Who can join

18 and older, any sex, with Pulmonary Embolism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

BACKGROUND: Pulmonary embolism (PE) is associated to high mortality rate worldwide. However, the diagnosis of PE often results inaccurate. Many cases of PE are incorrectly diagnosed or missed and they are often associated to sudden unexpected death (SUD). In forensic practice, it is important to establish the time of thrombus formation in order to determine the precise moment of death. The autopsy remains the gold standard method for the identification of death cause allowing the determination of discrepancies between clinical and autopsy diagnoses. The aim of our study will be to verify the morphological and histological criteria of fatal cases of PE and evaluate the dating of thrombus formation considering 5 ranges of time. METHODS: Pulmonary vessels sections will be collected from January 2010 to December 2017. Sections of thrombus sampling will be stained with hematoxylin and eosin. The content of infiltrated cells, fibroblasts and collagen fibers will be scored using a semi-quantitative three-point scale of range values. Hypothesis: After a macroscopic observation and a good sampling traditional histology, it will be important to identify the time of thrombus formation. We will identify histologically a range of time in the physiopathology of the thrombus (early, recent, recent-medium, medium, old), allowing to determine the dating of thrombus formation and the exact time of death.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The dating of thrombus organization in cases of pulmonary embolism: an autopsy study.
Mansueto G, Costa D, Capasso E, Varavallo F, et al · · 2019 · cited 32× · PMID 31703628 · DOI 10.1186/s12872-019-1219-8

Verify or expand the search:

Other recruiting trials for Pulmonary Embolism

Currently open trials in the same condition.

NCT07381712 — High-Flow Nasal Cannula Versus Non-Invasive Ventilation for Acute Respiratory Failure in Pulmonary Embolism. · NA · active not recruiting
NCT04211181 — CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism · NA · recruiting
NCT07003646 — Reperfusion Treatment in Acute Pulmonary Embolism · recruiting
NCT06600542 — Inari VISION Registry · recruiting
NCT06622876 — Incidental Discovery of Pulmonary Emboli Via CT Scan: Impact of Detections on Patient Care and Resulting Complications · recruiting

Other University of Campania Luigi Vanvitelli trials

Trials by the same sponsor.

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NCT07124676 — Prospective Study Comparing Two Classification Systems for Second-degree Vaginal Tears During Spontaneous Childbirth to · not yet recruiting
NCT07425912 — Real-World Evaluation of TouchCare Nano in Pediatric Type 1 Diabetes · active not recruiting
NCT06991816 — The Brain&Senses Study · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03887819 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Campania Luigi Vanvitelli
Last refreshed: 26 March 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03887819.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing