Last reviewed · How we verify
NCT03880162: CaPrO
Metabolic Effects of a Low Carbohydrate Versus a Standard Diet in Morbidly Obese With Prediabetes
NA trial testing Low carbohydrate diet in PreDiabetes in 20 participants. Completed in 3 May 2024.
3 May 2024
Quick facts
| Lead sponsor | Insel Gruppe AG, University Hospital Bern |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 13 May 2019 |
| Primary completion | 3 May 2024 |
| Estimated completion | 3 May 2024 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Low carbohydrate diet
- Energy-matched standard diet
Conditions studied
- PreDiabetes — all drugs for PreDiabetes →
- Obesity, Morbid — all drugs for Obesity, Morbid →
- Bariatric Surgery Candidate — all drugs for Bariatric Surgery Candidate →
Sponsor
Insel Gruppe AG, University Hospital Bern
Who can join
18 and older, any sex, with PreDiabetes or Obesity, Morbid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To investigate the metabolic effects of a low carbohydrate versus energy-matched standard diet in morbidly obese individuals with prediabetes awaiting bariatric surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy-matched standard diet.
Stone J, Tripyla A, Scalise MC, Balmer ML, et al · · 2026 · cited 1× · PMID 41395693 · DOI 10.1111/dom.70364
Verify or expand the search:
- PubMed search for NCT03880162
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Low carbohydrate diet
Trials testing the same drug.
- NCT05872711 — Low Carbohydrate Versus Mediterranean Diet in Adolescents With Type 1 Diabetes · NA · unknown
- NCT05094505 — Isolated and Combined Effect of a Low Carbohydrate Diet and Exercise in Hypoxia in Patients With Type 2 Diabetes · NA · completed
- NCT04614168 — Maximising Time With a Normal Blood Glucose to Restore the Glucagon Response in Type 1 Diabetes · NA · completed
- NCT04213300 — Low Carbohydrate Diet, Glycaemic Control and Quality of Life in Australian Adults With Type 1 Diabetes · completed
- NCT04228822 — Safety and Feasibility of a Low Carbohydrate Diet in Children With Type 1 Diabetes · NA · completed
Other recruiting trials for PreDiabetes
Currently open trials in the same condition.
- NCT06897982 — Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center · NA · recruiting
- NCT06967558 — The Role of Islet GLP-1 in the Pathogenesis of Prediabetes · Phase 2 · recruiting
- NCT06482944 — Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes · NA · recruiting
- NCT06989164 — Post Prandial Individual Responses to Different Foods · NA · recruiting
- NCT07254572 — Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes · Phase 4 · recruiting
Other Insel Gruppe AG, University Hospital Bern trials
Trials by the same sponsor.
- NCT06546384 — GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Disease · NA · not yet recruiting
- NCT07524049 — Giving Children a Voice in Paediatric Anaesthesia · not yet recruiting
- NCT07415668 — Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning · NA · not yet recruiting
- NCT07478536 — Stockholm3 Test Validation in Men on Active Surveillance in Switzerland (CHAS3 Trial) · not yet recruiting
- NCT07201506 — Real-Time Intracardiac Echocardiography for Ventricular Arrhythmia Ablation · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03880162 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Insel Gruppe AG, University Hospital Bern
- Last refreshed: 9 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03880162.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing