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NCT03879590
Efficacy Of Doxophylline As A Sparing Treatment For Inhaled Corticosteroids In Mexican Children With Asthma
Phase 3 trial testing Doxophylline in Asthma Chronic in 60 participants. Status unknown.
1 September 2019
Quick facts
| Lead sponsor | Universidad Autonoma de Nuevo Leon |
|---|---|
| Phase | Phase 3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 May 2019 |
| Primary completion | 1 September 2019 |
| Estimated completion | 1 December 2019 |
Drugs / interventions tested
- Doxophylline — full drug profile →
- Budesonide (BUDESONIDE) — full drug profile →
Conditions studied
- Asthma Chronic — all drugs for Asthma Chronic →
- Asthma in Children — all drugs for Asthma in Children →
Sponsor
Universidad Autonoma de Nuevo Leon — full company profile →
Who can join
Adults 6 to 16, any sex, with Asthma Chronic or Asthma in Children. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Changes in the values of the forced expiratory volume on the first second
Time frame: 4 weeks
Changes in the values of FEV1 (FEV1 in percent predicted) by comparing the baseline to subsequent evaluations.
Sponsor's own description
This study evaluated the efficacy of doxophylline as a steroid sparing treatment in Mexican children with asthma treated with medium ir high doses of inhaled corticosteroids (ICS). It is a cross over study in which both groups of patients will receive doxophylline plus a lower steroid dose maintaining the same treatment step according to GINA guidelines, one group will maintain the same treatment dose while the other will start with doxophylline with the lower ICS dose, and by the middle of the study both groups will interchange treatment schemes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03879590
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other recruiting trials for Asthma Chronic
Currently open trials in the same condition.
- NCT06273072 — Metformin IN Asthma for Overweight and Obese Individuals (MINA) · Phase 2 · recruiting
- NCT06377345 — Remote Patient Monitoring Solution for Chronic Respiratory Disease Management · NA · recruiting
- NCT05572177 — Feasibility of a Smartphone Application for Asthma Self-management · NA · recruiting
Other Universidad Autonoma de Nuevo Leon trials
Trials by the same sponsor.
- NCT07449000 — Losartan for Corneal Fibrosis · NA · recruiting
- NCT07497555 — Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-G · NA · recruiting
- NCT06824922 — "Educational Intervention 'Be Yourself': Digital Innovation to Prevent Teenage Pregnancy" · NA · not yet recruiting
- NCT06861478 — PPIs and In-Hospital Morbidity in Acute Variceal Bleeding With Chronic Liver Disease · Phase 2 · recruiting
- NCT06617299 — Cognitive-behavioral Intervention to Increase the Practice of Responsive Feeding and Maintain Healthy Weight in Infants · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03879590 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Autonoma de Nuevo Leon
- Last refreshed: 14 March 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03879590.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing