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NCT03878888
Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control
Phase 4 trial testing Exparel 266 MG Per 20 ML Injection in Postoperative Pain in 52 participants. Completed in 1 July 2019.
1 July 2019
Quick facts
| Lead sponsor | St. Luke's Hospital, Pennsylvania |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 52 |
| Start date | 15 January 2019 |
| Primary completion | 1 July 2019 |
| Estimated completion | 1 July 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Exparel 266 MG Per 20 ML Injection — full drug profile →
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
- Surgery — all drugs for Surgery →
- Anesthesia, Local — all drugs for Anesthesia, Local →
Sponsor
St. Luke's Hospital, Pennsylvania
Who can join
18 and older, any sex, with Postoperative Pain or Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To determine if Exparel (Liposomal Bupivacaine, an FDA approved drug) use in ultrasound guided Transversus Abdominis Plane (TAP) blocks may reduce opioid requirement use postoperatively, reduce pain scores postoperatively, reduce incidence of nausea in the postop period, and decrease length of hospital stay
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03878888
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Exparel 266 MG Per 20 ML Injection
Trials testing the same drug.
- NCT06465992 — Liposomal Bupivacaine With Dexamethasone for Foot Surgery · Phase 4 · enrolling by invitation
- NCT03743194 — Pectoralis and Serratus Muscle Blocks · Phase 4 · completed
- NCT03196505 — The Effect of Liposomal Bupivacaine on Post Operative Pain and Narcotic Use After Bariatric Surgery · Phase 4 · completed
Other recruiting trials for Postoperative Pain
Currently open trials in the same condition.
- NCT07452120 — DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery · NA · recruiting
- NCT07396688 — Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients · NA · recruiting
- NCT07413055 — Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Sur · Phase 3 · recruiting
- NCT07496086 — External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative · NA · recruiting
- NCT07396545 — External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastr · NA · recruiting
Other St. Luke's Hospital, Pennsylvania trials
Trials by the same sponsor.
- NCT06029582 — VR Headset for Pain During Pregnancy Termination · NA · unknown
- NCT06806410 — The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery · Phase 4 · active not recruiting
- NCT05494645 — Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery: A Randomized Controlled Trial · Phase 4 · unknown
- NCT04910165 — Exparel Use in Adductor Canal Block After Total Knee Arthroplasty · Phase 3 · completed
- NCT03953404 — POC SPLA2-IIA as a Biomarker for Sepsis and Septic Shock · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03878888 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Luke's Hospital, Pennsylvania
- Last refreshed: 17 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03878888.
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