NCT03878836

Follow-up of Persons With Multiple Sclerosis

Status unknown Last updated 18 March 2019

What this trial tests

trial testing Routine assessments in Multiple Sclerosis in 118 participants. Status unknown.

Timeline

1 October 2016

Primary endpoint
1 August 2021

1 August 2021

Quick facts

Lead sponsor	Dokuz Eylul University
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	118
Start date	1 October 2016
Primary completion	1 August 2021
Estimated completion	1 August 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Routine assessments

Conditions studied

• Multiple Sclerosis — all drugs for Multiple Sclerosis →

Sponsor

Dokuz Eylul University

Who can join

18 and older, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Multiple sclerosis (MS) is a chronic, progressive and demyelinating disease that affects more than 2.5 million people in the world and is frequently seen in young adults between 20 and 40 years of age, especially in women. Although the exact MS in Turkey is not known, it is estimated as 40/100,000. According to epidemiological studies in recent years, the prevalence and incidence of MS tend to increase. The most common clinical signs and symptoms include loss of sensation in the extremities, partial or total vision loss, acute or subacute motor dysfunction, cognitive impairment, double vision and gait dysfunction.

Currently, MS has no definitive cure. Progressive symptoms related to the disease need to be managed in order to increase and maintain the quality of life of individuals with MS. Pharmacological, physiotherapeutic and psychotherapeutic methods are the most effective effective methods in the management of symptoms. However, the efficacy of these methods has been demonstrated in clinical trials. The outcomes cannot be generalized to the entire MS population because of the inclusion and exclusion criteria that exist in clinical trials. In addition, clinical trials are conducted at a specified time interval (usually a short time interval is selected) and generally, short-term results are provided. In order to better understanding the course of MS, it is of utmost importance that long-term follow-up studies are carried out where as many patients are included and patients are followed from the date of initial diagnosis. The aim of this study is to investigate the change of physical, psychosocial and cognitive characteristics over time and the correlated variables.

The volunteers from MS patients who attend routine control of the MS outpatient clinic of Dokuz Eylül University Hospital will participate in the study. Physical and clinical assessments will be performed by physicians and physiotherapists, and cognitive evaluations will be performed by psychologists with 6-month intervals.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Discriminative ability of the original and short form of the Activities-specific Balance Confidence scale and its individual items for falls in people with multiple sclerosis.
   Abasıyanık Z, Kahraman T, Baba C, Sağıcı Ö, et al · · 2024 · cited 2× · PMID 38483733 · DOI 10.1007/s13760-024-02515-y