The Trauma INtramuscular Tranexamic Acid Clinical Trial (TraumaINTACT)

NCT03875937 PHASE1, PHASE2 COMPLETED

Intramuscular injection of tranexamic acid (TXA) would increase its use in situations where administration of intravenous drugs is difficult. The investigators aim to assess the population pharmacokinetics of intramuscular TXA in trauma patients. Primary endpoint: Serum TXA concentrations over time. Secondary endpoints: Local reactions at injection sites and adverse events

Details

Lead sponsor	London School of Hygiene and Tropical Medicine
Phase	PHASE1, PHASE2
Status	COMPLETED
Enrolment	31
Start date	Tue Sep 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Wed Feb 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Traumatic Haemorrhage

Interventions

• Tranexamic 1 gram

Countries

United Kingdom