NCT03872583: UMIMS

Understanding Magnetic Resonance Imaging in Multiple Sclerosis

Completed NA Last updated 3 January 2024

What this trial tests

NA trial testing Understanding MRI in MS (website) in Multiple Sclerosis in 120 participants. Completed in 1 December 2022.

Timeline

15 March 2019

Primary endpoint
1 December 2022

1 December 2022

Quick facts

Lead sponsor	Universitätsklinikum Hamburg-Eppendorf
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	other
Enrollment	120
Start date	15 March 2019
Primary completion	1 December 2022
Estimated completion	1 December 2022
Sites	1 location across Germany

Drugs / interventions tested

• Understanding MRI in MS (website)
• Control website

Conditions studied

• Multiple Sclerosis — all drugs for Multiple Sclerosis →
• Multiple Sclerosis, Relapsing-Remitting — all drugs for Multiple Sclerosis, Relapsing-Remitting →
• Clinically Isolated Syndrome — all drugs for Clinically Isolated Syndrome →

Sponsor

Universitätsklinikum Hamburg-Eppendorf — full company profile →

Who can join

Adults 18 to 65, any sex, with Multiple Sclerosis or Multiple Sclerosis, Relapsing-Remitting. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Magnetic resonance imaging (MRI) results play a major role in the lives of people with multiple sclerosis (pwMS). Even though MRI is used for diagnosis, prognosis and therapy control, pwMS' knowledge concerning this complex matter is scarce. Without adequate disease-specific knowledge, pwMS cannot truly make an informed choice when considering their MRI results (e.g. necessity of future MRI scans or therapy change).

The investigators have developed an innovative, evidence-based and interactive online education tool called "Understanding MRI in MS", which incorporates all relevant information about MRI in MS and its implications in disease management.

In this randomized, controlled and double-blind trial the tool's effect on MRI-specific knowledge, self-perceived competence and involvement in medical decision, that are based on MRI results will be assessed.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Assessing the effect of an evidence-based patient online educational tool for people with multiple sclerosis called UMIMS-understanding magnetic resonance imaging in multiple sclerosis: study protocol for a double-blind, randomized controlled trial.
   Schiffmann I, Freund M, Vettorazzi E, Stellmann JP, et al · · 2020 · cited 3× · PMID 33298133 · DOI 10.1186/s13063-020-04855-5
2. Understanding Magnetic Resonance Imaging in Multiple Sclerosis (UMIMS): Development and Piloting of an Online Education Program About Magnetic Resonance Imaging for People With Multiple Sclerosis.
   Freund M, Schiffmann I, Rahn AC, Chard D, et al · · 2022 · cited 2× · PMID 35418941 · DOI 10.3389/fneur.2022.856240
3. Understanding magnetic resonance imaging in multiple sclerosis (UMIMS) and accompanying process evaluation: study protocol for a double-blind, randomized controlled trial using an evidence-based patient information website
   Schiffmann I, Freund M, Vettorazzi E, Stellmann J, et al · · 2020 · DOI 10.21203/rs.2.24184/v1