Who is sponsoring NCT03871998?

NCT03871998 is sponsored by University College Cork.

What drugs are being tested in NCT03871998?

Interventions in NCT03871998: Skin barrier protection in the first 2 months of life.

What condition does NCT03871998 study?

NCT03871998 studies Eczema Atopic Dermatitis, Eczema, Eczema, Infantile, Food Allergy.

Is NCT03871998 still recruiting?

NCT03871998 is currently completed. Last updated 22 June 2022.

Last reviewed 2022-06-22 · How we verify

NCT03871998: STOP AD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Short-term Topical Application to Prevent Atopic Dermatitis

Completed NA Last updated 22 June 2022

What this trial tests

NA trial testing Skin barrier protection in the first 2 months of life in Eczema Atopic Dermatitis in 321 participants. Completed in 30 November 2021.

Timeline

16 April 2019

Primary endpoint
30 November 2021

30 November 2021

Quick facts

Lead sponsor	University College Cork
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	321
Start date	16 April 2019
Primary completion	30 November 2021
Estimated completion	30 November 2021
Sites	1 location across Ireland

Drugs / interventions tested

Skin barrier protection in the first 2 months of life

Conditions studied

Eczema Atopic Dermatitis — all drugs for Eczema Atopic Dermatitis →
Eczema — all drugs for Eczema →
Eczema, Infantile — all drugs for Eczema, Infantile →
Food Allergy — all drugs for Food Allergy →

Sponsor

University College Cork

Who can join

Adults 0 Days to 5 Days, any sex, with Eczema Atopic Dermatitis or Eczema. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a randomised, open-label, controlled study designed to investigate the effect of short-term neonatal skin barrier protection using a commercially available moisturiser on the prevention of atopic dermatitis and food allergy in high risk children.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented?
Brough HA, Nadeau KC, Sindher SB, Alkotob SS, et al · · 2020 · cited 179× · PMID 32249942 · DOI 10.1111/all.14304
Early initiation of short-term emollient use for the prevention of atopic dermatitis in high-risk infants-The STOP-AD randomised controlled trial.
Ní Chaoimh C, Lad D, Nico C, Puppels GJ, et al · · 2023 · cited 63× · PMID 35997592 · DOI 10.1111/all.15491
Skin care interventions in infants for preventing eczema and food allergy.
Kelleher MM, Cro S, Cornelius V, Lodrup Carlsen KC, et al · · 2021 · cited 43× · PMID 33545739 · DOI 10.1002/14651858.cd013534.pub2
Skin care interventions in infants for preventing eczema and food allergy.
Kelleher MM, Phillips R, Brown SJ, Cro S, et al · · 2022 · cited 29× · PMID 36373988 · DOI 10.1002/14651858.cd013534.pub3
Clinical Measurement of Transepidermal Water Loss.
Kundu D, Jayaraman A, Sen CK. · · 2026 · cited 4× · PMID 40476522 · DOI 10.1089/wound.2024.0148
Early initiation of short-term emollient use for the prevention of atopic dermatitis in high risk infants -- the STOP AD randomised controlled trial
Hourihane J, Chaoimh CN, Lad D, Nico C, et al · · 2022 · DOI 10.22541/au.164940311.12725370/v1

Verify or expand the search:

Other recruiting trials for Eczema Atopic Dermatitis

Currently open trials in the same condition.

NCT07355075 — A Study to Assess the Efficacy of GX-03 in Moderate to Severe Eczema (Atopic Dermatitis) · Phase 2 · recruiting

Other University College Cork trials

Trials by the same sponsor.

NCT07481240 — A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families · NA · recruiting
NCT06857539 — Assessing Intellectual and Motor Outcomes in High-risk Infants · not yet recruiting
NCT07363928 — A Digital Cognitive Behavioural Therapy for Insomnia Intervention in Mild Cognitive Impairment and Mild Dementia · NA · completed
NCT06705582 — OASIS Study: Vitamin D Deficiency Prevention Among Older Adults in Ireland · NA · completed
NCT06709209 — AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03871998 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University College Cork
Last refreshed: 22 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03871998.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing