NCT03870061

Evaluation of an Infant Immunization Encouragement Program in Nigeria

Completed NA Last updated 31 March 2020

What this trial tests

NA trial testing All Babies Are Equal Initiative (conditional cash transfer program) in Tuberculosis in 5,187 participants. Completed in 20 February 2020.

Timeline

1 July 2018

Primary endpoint
20 February 2020

20 February 2020

Quick facts

Lead sponsor	GiveWell
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	5,187
Start date	1 July 2018
Primary completion	20 February 2020
Estimated completion	20 February 2020
Sites	3 locations across Nigeria

Drugs / interventions tested

• All Babies Are Equal Initiative (conditional cash transfer program)

Conditions studied

• Tuberculosis — all drugs for Tuberculosis →
• Diphtheria — all drugs for Diphtheria →
• Tetanus — all drugs for Tetanus →
• Pertussis — all drugs for Pertussis →

Sponsor

GiveWell

Who can join

Adults 12 Months to 16 Months, any sex, with Tuberculosis or Diphtheria. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Previous studies have shown that a small incentive can have a large impact on health behaviors like vaccinating children. New Incentives, an international non-governmental organization (NGO), aims to boost demand for immunization by offering cash incentives to caregivers who have their child vaccinated at a program clinic. In collaboration with New Incentives, IDinsight is conducting a study to see whether this approach will increase immunization in North West Nigeria. This study aims to investigate whether giving cash to caregivers in North West Nigeria who bring their infants to receive vaccination against common infections (tuberculosis, diphtheria, tetanus, pertussis, hepatitis B virus (HBV) infection, Haemophilus influenzae Type B (Hib), pneumococcal bacteria, measles, rotavirus, polio, yellow fever) increases the proportion of children who are immunized. The study's main hypothesis is that New Incentives' program will increase the percentage of children immunized with BCG, any PENTA, or Measles 1 by an average increase of at least 7-percentage points across all program clinics that share a similar profile to the clinics New Incentives will operate in at scale. The study is taking place in Jigawa, Katsina, and Zamfara States between August 2017 and January 2020.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Development of nucleic acid-based vaccines against dengue and other mosquito-borne flaviviruses: the past, present, and future.
   Bello MB, Alsaadi A, Naeem A, Almahboub SA, et al · · 2024 · cited 13× · PMID 39840044 · DOI 10.3389/fimmu.2024.1475886