Last reviewed · How we verify
NCT03867214
Effects of Oral Care With Glutamine on Oral Health, Oral Flora and Incidence of Pneumonia After Neurosurgery With Microbiome Analysis
Phase 4 trial testing Glutamine in Oral Mucositis in 100 participants. Status unknown.
1 March 2021
Quick facts
| Lead sponsor | Yanzhao |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 January 2019 |
| Primary completion | 1 March 2021 |
| Estimated completion | 1 March 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Glutamine (GLUTAMINE) — full drug profile →
- Normal saline
Conditions studied
- Oral Mucositis — all drugs for Oral Mucositis →
- Pneumonia — all drugs for Pneumonia →
Sponsor
Yanzhao
Who can join
Adults 18 to 80, any sex, with Oral Mucositis or Pneumonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized, double-blind, single-center and controlled study comparing the efficacy and safety of intravenous administration of tranexamic acid to reduce blood loss in simultaneous bilateral total knee arthroplasty.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effectiveness of Glutamine Oral Care in Reducing Oral Mucositis and Improving Oral Health After Neurosurgery: A Randomized Controlled Trial with Microbiome Analysis.
Gao Y, Yang H, Zhang X, Ma Y, et al · · 2024 · PMID 38384124 · DOI 10.12659/msm.942585
Verify or expand the search:
- PubMed search for NCT03867214
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Glutamine
Trials testing the same drug.
- NCT06617182 — Efficacy and Safety of Thalidomide Combined With Glutamine in the Treatment of Radiation Intestinal Injury. · Phase 2 · recruiting
- NCT05655819 — A Study of Glutamine to Treat Intestinal Permeability in Functional Dyspepsia · Phase 1, PHASE2 · completed
- NCT05569993 — Glutamine and Traumatic Brain Injury · EARLY_PHASE1 · unknown
- NCT05856188 — Efficacy of Glutamine in Management of Radiation Mucositis · NA · unknown
- NCT04909905 — Glutamine Supplementation and Short-term Mortality in Covid-19 · Phase 3 · completed
Other recruiting trials for Oral Mucositis
Currently open trials in the same condition.
- NCT07491536 — Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis · NA · recruiting
- NCT07400328 — Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients · Phase 2 · recruiting
- NCT06525402 — Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemothe · NA · recruiting
- NCT06315855 — F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors) · NA · recruiting
- NCT05966194 — RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03867214 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yanzhao
- Last refreshed: 27 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03867214.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing