NCT03866850

Degenerative Consequences of Congenital Deafness

Terminated Last updated 7 April 2023

What this trial tests

trial testing Phase duration in Congenital Deafness in 34 participants. Terminated before completion.

Timeline

1 August 2019

Primary endpoint
4 April 2023

4 April 2023

Quick facts

Lead sponsor	East Carolina University
Status	Terminated
Study type	OBSERVATIONAL
Enrollment	34
Start date	1 August 2019
Primary completion	4 April 2023
Estimated completion	4 April 2023
Sites	1 location across United States

Drugs / interventions tested

• Phase duration

Conditions studied

• Congenital Deafness — all drugs for Congenital Deafness →

Sponsor

East Carolina University

Who can join

15 and older, any sex, with Congenital Deafness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this study, the investigators will study one of the basic biophysical properties of the auditory nerve, charge integration, behaviorally (detection threshold versus phase duration functions). The investigators will compare charge integration in two subject groups: congenitally deafened and deafened at a later age in life. The investigators will then examine if behaviorally estimated neural excitation patterns differ between short phase duration and long phase duration stimulation. Lastly, The investigators will measure if speech recognition improves with using long phase duration stimulation, relative to using the standard default short phase duration stimulation. The primary endpoint of the study is speech recognition, and the secondary endpoints are the steepness of the detection threshold versus phase duration functions, and the width of psychophysically estimated neural excitation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.