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NCT03864380: MARETINE
Analysis of the Variation of the Retinal Vascularization After a Prolonged Effort
trial testing Color retinography in Retinal Vascular Disorder in 29 participants. Completed in 6 May 2019.
14 April 2019
Quick facts
| Lead sponsor | Fondation Ophtalmologique Adolphe de Rothschild |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 29 |
| Start date | 15 March 2019 |
| Primary completion | 14 April 2019 |
| Estimated completion | 6 May 2019 |
| Sites | 1 location across France |
Drugs / interventions tested
- Color retinography
- OCT-A
- Blood pressure measurement
Conditions studied
- Retinal Vascular Disorder — all drugs for Retinal Vascular Disorder →
- Sport Injury — all drugs for Sport Injury →
Sponsor
Fondation Ophtalmologique Adolphe de Rothschild — full company profile →
Who can join
18 and older, any sex, with Retinal Vascular Disorder or Sport Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization. The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition. The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise. This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date. The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized. the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Retinal and choroidal blood flow variations after an endurance exercise: A real-life pilot study at the Paris Marathon.
Mauget-Faÿsse M, Arej N, Paternoster M, Zuber K, et al · · 2021 · cited 11× · PMID 33824079 · DOI 10.1016/j.jsams.2021.03.013
Verify or expand the search:
- PubMed search for NCT03864380
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03864380 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fondation Ophtalmologique Adolphe de Rothschild
- Last refreshed: 7 May 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03864380.
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