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NCT03861260: GUARDIAN
GAG Replacement vs URethral DIlAtatioN
NA trial testing Rigid cystoscopy with urethral dilatation in Recurrent Urinary Tract Infection. Withdrawn.
28 October 2019
Quick facts
| Lead sponsor | Hampshire Hospitals NHS Foundation Trust |
|---|---|
| Phase | NA |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Start date | 30 April 2019 |
| Primary completion | 28 October 2019 |
| Estimated completion | 28 October 2019 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Rigid cystoscopy with urethral dilatation
- Flexible cystoscopy and installation of Glycosaminoglycan layer replacement (laluril)
Conditions studied
- Recurrent Urinary Tract Infection — all drugs for Recurrent Urinary Tract Infection →
Sponsor
Hampshire Hospitals NHS Foundation Trust
Who can join
Eligibility, female only, with Recurrent Urinary Tract Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this randomised parallel trial is to compare the efficacy of Glycosaminoglycan layer replacement against cystoscopy and urethral dilatation in the treatment of recurrent urinary tract infection in pre-menopausal women. The women will be randomised to 1 of 2 arms.Arm 1 patients will receive standard treatment from the Urologists. This will involve rigid cystoscopy and urethral dilatation, under general anaesthetic. Arm 2 patients will receive standard treatment from the Gynaecologists.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03861260
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Recurrent Urinary Tract Infection
Currently open trials in the same condition.
- NCT06940622 — A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections · NA · recruiting
- NCT06124820 — RCT Comparing Intravaginal Laser Therapy to Sham in Post-menopausal Women with Recurrent Urinary Tract Infections · NA · active not recruiting
- NCT06050148 — Faecal Microbiota Transplantation as Means of Preventing Recurrent Urinary Tract Infections · Phase 2, PHASE3 · recruiting
- NCT05553652 — The Effect of ASTARTE™ on Recurrent Urinary Tract Infection · NA · recruiting
- NCT04807894 — Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo · Phase 4 · recruiting
Other Hampshire Hospitals NHS Foundation Trust trials
Trials by the same sponsor.
- NCT03995797 — VESPER: Pelvic Organ Prolapse Study · NA · withdrawn
- NCT05630092 — Comparing 6-Minute Walk Tests for Ambulatory Oxygen Assessment · NA · completed
- NCT03996070 — VESPER: Stress Urinary Incontinence STUDY · NA · completed
- NCT05718726 — Post Splenectomy Infections After Surgery for Peritoneal Malignancies (OPSI) · recruiting
- NCT03317145 — Lower Limb Blood Flow Geko vs Foot Pump · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03861260 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hampshire Hospitals NHS Foundation Trust
- Last refreshed: 27 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03861260.
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