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NCT03860675

Assessment of Walking-related Fatigability in Patients With Multiple Sclerosis.

Completed NA Last updated 4 March 2019
What this trial tests

NA trial testing Assessment of walking-related fatigability in Multiple Sclerosis in 85 participants. Completed in 31 May 2018.

Timeline
1 December 2017
Primary endpoint
31 May 2018
31 May 2018

Quick facts

Lead sponsorHasselt University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposescreening
Enrollment85
Start date1 December 2017
Primary completion31 May 2018
Estimated completion31 May 2018
Sites3 locations across Belgium

Drugs / interventions tested

Conditions studied

Sponsor

Hasselt University

Who can join

Adults 18 to 70, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary goal of this interventional study is to objectively examine the prevalence of walking-related performance fatigability, together with the psychometric properties of its measuring parameters. The secondary aim is to investigate the relation of other clinical symptoms to walking-related performance fatigability. The following three research questions will be addressed: 1. How prevalent is walking-related performance fatigability and what are the psychometric properties of fatigability formulas in preparation of use as experimental outcome measure? 2. What are associated symptoms of walking-related motor fatigability and how long does this manifest? 3. What is the relationship between cognitive fatigability and walking-related performance fatigability? participants perform two six-minute walking test (6MWT), with 3-5 days in between. Before and after the 6MWT, three screenings test (spasticity, muscle strength, balance) are executed and the participants have to indicate the severity of eleven possible symptoms (= symptom inventory, SI) on a VAS scale. These screening tests and SI are continued every 10 minutes for half an hour. During a third test session, participants perform a 6-minute vigilance alphabet test in rest and while doing a 6MWT to investigate the relationship between cognitive and motor fatigability.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Multiple Sclerosis

Currently open trials in the same condition.

Other Hasselt University trials

Trials by the same sponsor.

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Data sources for this page

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