NCT03860194

Effects of Dietary Supplements on Sarcopenic Elders

Completed NA Last updated 20 March 2019

What this trial tests

NA trial testing Protison with High Protein 51(Original Flavor) in Sarcopenia in 85 participants. Completed in 30 December 2017.

Timeline

22 March 2017

Primary endpoint
30 December 2017

30 December 2017

Quick facts

Lead sponsor	Far Eastern Memorial Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	85
Start date	22 March 2017
Primary completion	30 December 2017
Estimated completion	30 December 2017
Sites	1 location across Taiwan

Drugs / interventions tested

• Protison with High Protein 51(Original Flavor)

Conditions studied

• Sarcopenia — all drugs for Sarcopenia →

Sponsor

Far Eastern Memorial Hospital

Who can join

Adults 65 to 95, any sex, with Sarcopenia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Sarcopenia is defined as a syndrome characterized by decline of skeletal muscle mass and strength or an alteration in physical function. Although some studies showed nutritional supplementation alone might have health benefits for older sarcopenic patients, the results were inconsistent and remain controversial. The objective of this study was to evaluate if a sufficient protein diet including supplements with leucine-enriched whey protein and vitamin D can lead to better improvement than sufficient dietary protein alone in maintaining muscle mass and strength among sarcopenic elders.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Effects of adequate dietary protein with whey protein, leucine, and vitamin D supplementation on sarcopenia in older adults: An open-label, parallel-group study.
   Lin CC, Shih MH, Chen CD, Yeh SL. · · 2021 · cited 73× · PMID 32928579 · DOI 10.1016/j.clnu.2020.08.017
2. Reply to the letter to the editor: Effects of adequate dietary protein with whey protein, leucine, and vitamin D supplementation on sarcopenia in older adults: An open-label, parallel-group study.
   Lin CC, Yeh SL. · · 2022 · cited 1× · PMID 35177293 · DOI 10.1016/j.clnu.2022.01.030