NCT03859505 is a NA clinical trial of Active PBMT in Low Back Pain, sponsored by Universidade Cidade de Sao Paulo.

Who is sponsoring NCT03859505?

NCT03859505 is sponsored by Universidade Cidade de Sao Paulo.

What drugs are being tested in NCT03859505?

Interventions in NCT03859505: Placebo PBMT, Active PBMT.

What condition does NCT03859505 study?

NCT03859505 studies Low Back Pain.

Is NCT03859505 still recruiting?

NCT03859505 is currently completed. Last updated 1 April 2019.

Last reviewed 2019-04-01 · How we verify

NCT03859505

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain

Completed NA Last updated 1 April 2019

What this trial tests

NA trial testing Placebo PBMT in Low Back Pain in 18 participants. Completed in 29 March 2019.

Timeline

18 March 2019

Primary endpoint
29 March 2019

29 March 2019

Quick facts

Lead sponsor	Universidade Cidade de Sao Paulo
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	18
Start date	18 March 2019
Primary completion	29 March 2019
Estimated completion	29 March 2019
Sites	1 location across Norway

Drugs / interventions tested

Placebo PBMT
Active PBMT

Conditions studied

Low Back Pain — all drugs for Low Back Pain →

Sponsor

Universidade Cidade de Sao Paulo

Who can join

Adults 18 to 65, any sex, with Low Back Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Low back pain (LBP) is ranked as one of the most prevalent health conditions. It is likely that some inflammatory mediators could be associated with pain and disability in these patients. Photobiomodulation therapy (PBMT) is a non-pharmacological therapy often used in patients with LBP that decrease release of inflammatory mediators and accelerate muscle repair in different muscle skeletal conditions, as mechanisms of action. The present research project aims to evaluate the effects of PBMT on systemic levels of inflammatory markers and levels of pain intensity in patients with chronic non-specific low back pain.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Photobiomodulation Therapy is Able to Modulate PGE<sub>2</sub> Levels in Patients With Chronic Non-Specific Low Back Pain: A Randomized Placebo-Controlled Trial.
Tomazoni SS, Costa LOP, Joensen J, Stausholm MB, et al · · 2021 · cited 17× · PMID 32330315 · DOI 10.1002/lsm.23255
Effects of photobiomodulation therapy on inflammatory mediators in patients with chronic non-specific low back pain: Protocol for a randomized placebo-controlled trial.
Tomazoni SS, Costa LOP, Joensen J, Stausholm MB, et al · · 2019 · cited 7× · PMID 30985704 · DOI 10.1097/md.0000000000015177

Verify or expand the search:

Other trials of Active PBMT

Trials testing the same drug.

NCT07511790 — Photobiomodulation on Performance in Female Futsal Athletes · NA · not yet recruiting
NCT07511803 — Photobiomodulation on Recovery in Female Futsal Athletes · NA · not yet recruiting
NCT06549660 — PBMT in Providing Temporary Relief of Low Back Pain of Musculoskeletal Origin · NA · recruiting
NCT04476095 — Photobiomodulation Therapy (PBMT) in Patients With Low Back Pain (LBP) · NA · unknown
NCT04322812 — Effects of Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With Fibromyalgia · NA · completed

Other recruiting trials for Low Back Pain

Currently open trials in the same condition.

NCT07526012 — Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome · NA · recruiting
NCT07535047 — Placebo-Induced Hypoalgesia During Transcutaneous Electrical Nerve Stimulation Application in Low Back Pain · NA · recruiting
NCT07463729 — Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome · NA · recruiting
NCT07250568 — Office Program Effects on Pain, Posture, Muscle Physiology, Stress, Ergonomics, and Quality of Life in LBP Workers · NA · recruiting
NCT07467070 — Effectiveness of Pilates on Postural Correction, Core Strength and Flexibility in Younger Individuals With Non-specific · NA · recruiting

Other Universidade Cidade de Sao Paulo trials

Trials by the same sponsor.

NCT05904925 — Pilates for the Prevention of Musculoskeletal Complaints During Pregnancy · NA · unknown
NCT05575089 — Inspiratory Muscle Training and Pulmonary Function in Patients Submitted to Bariatric Surgery · NA · completed
NCT04274439 — Effectiveness and Cost-Effectiveness of a Tele-Rehabilitation Program in the Treatment of Chronic Musculoskeletal Pain · NA · unknown
NCT04114422 — A Seven-day Preoperative Exercise Training Program in People With Abdominal Cancer · NA · withdrawn
NCT03896672 — Clinical Implementation of the Use of Positive Pressure in Chest Drainage · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03859505 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidade Cidade de Sao Paulo
Last refreshed: 1 April 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03859505.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing