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NCT03855891: CT-CA-miRNA

Micro-RNA Profile in Patients With Different Stages of Atherosclerosis According to CTA

Completed NA Last updated 22 December 2020
What this trial tests

NA trial testing blood test in Ischemic Heart Disease in 81 participants. Completed in 1 October 2020.

Timeline
1 January 2019
Primary endpoint
14 August 2020
1 October 2020

Quick facts

Lead sponsorI.M. Sechenov First Moscow State Medical University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment81
Start date1 January 2019
Primary completion14 August 2020
Estimated completion1 October 2020
Sites1 location across Russia

Drugs / interventions tested

Conditions studied

Sponsor

I.M. Sechenov First Moscow State Medical University

Who can join

Adults 18 to 80, any sex, with Ischemic Heart Disease or Atherosclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main purpose of this single-center study is to determine the spectrum and levels of cardiospecific circulating microRNAs in patients with different stages of atherosclerosis according to 640-slice multispiral computed tomography (MSCT).

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Promising Directions in Atherosclerosis Treatment Based on Epigenetic Regulation Using MicroRNAs and Long Noncoding RNAs.
    Skuratovskaia D, Vulf M, Komar A, Kirienkova E, et al · · 2019 · cited 42× · PMID 31212708 · DOI 10.3390/biom9060226
  2. Network Medicine: A Clinical Approach for Precision Medicine and Personalized Therapy in Coronary Heart Disease.
    Infante T, Del Viscovo L, De Rimini ML, Padula S, et al · · 2020 · cited 30× · PMID 31723086 · DOI 10.5551/jat.52407
  3. Extracellular Non-Coding RNAs in Cardiovascular Diseases.
    Jiapaer Z, Li C, Yang X, Sun L, et al · · 2023 · cited 14× · PMID 36678784 · DOI 10.3390/pharmaceutics15010155
  4. Integrative Perspectives on Atherosclerosis: From Molecular Mechanisms to Therapeutic Approaches.
    Alrahimi JS, Ahmed FA, Haneef AA, Atar D. · · 2025 · PMID 41163826 · DOI 10.4103/sjmms.sjmms_18_25

Verify or expand the search:

Other trials of blood test

Trials testing the same drug.

Other recruiting trials for Ischemic Heart Disease

Currently open trials in the same condition.

Other I.M. Sechenov First Moscow State Medical University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03855891.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing