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NCT03854812
Magnesium Sulphate Versus Fentanyl Sedation During Burr-hole Surgery
Phase 2 trial testing Magnesium Sulphate in Monitored Anesthesia Care in 32 participants. Completed in 12 October 2019.
12 October 2019
Quick facts
| Lead sponsor | Kasr El Aini Hospital |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 32 |
| Start date | 1 March 2019 |
| Primary completion | 12 October 2019 |
| Estimated completion | 12 October 2019 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Magnesium Sulphate
- Fentanyl (fentanyl) — full drug profile →
- Propofol (Propofol) — full drug profile →
Conditions studied
- Monitored Anesthesia Care — all drugs for Monitored Anesthesia Care →
Sponsor
Kasr El Aini Hospital
Who can join
50 and older, any sex, with Monitored Anesthesia Care. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
MgSO4 was found to reduce the perioperative anesthetic and analgesic requirements when used as an adjuvant to general anesthesia. Fentanyl is a potent opioid and used as adjuvant to other sedatives in awake craniotomy procedure. No study, to the best of our knowledge had evaluated fentanyl continuous infusion, nor MgSo4 infusion as adjuvant sedative agents to propofol during Burr-hole surgery. The aim of this study is to evaluate and compare MgSO4 versus fentanyl continuous infusions for conscious sedation in patients undergoing burr hole surgery for evacuation of subdural hematoma with local infiltration.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03854812
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Magnesium Sulphate
Trials testing the same drug.
- NCT07326397 — Comparison Between Intrathecal Magnesium Sulphate & Dexmedetomidine in DHS · Phase 3 · not yet recruiting
- NCT05164627 — Dexmedetomidine Versus Magnesium Infusion in Reducing Agitations in Pediatric Patients Undergoing Adenotonsillectomy · NA · unknown
- NCT04393610 — Improving Quality of Bier Block · Phase 2, PHASE3 · unknown
- NCT03640390 — Dexmedetomidine Versus Magnesium Sulfate Infusion During Spinal Anesthesia · Phase 3 · completed
- NCT03461328 — Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal · Phase 4 · completed
Other recruiting trials for Monitored Anesthesia Care
Currently open trials in the same condition.
- NCT07413848 — qNOX Response to Nociceptive Motor Events During Procedural Sedation · recruiting
- NCT07022951 — The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes · recruiting
Other Kasr El Aini Hospital trials
Trials by the same sponsor.
- NCT07438652 — Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT · NA · recruiting
- NCT07488039 — Labroplasty in Cases of Anterior Shoulder Instability With Subcritical Glenoid Bone Loss · NA · recruiting
- NCT07274280 — Comparative Evaluation of Ambu AuraGain, LarySeal Pro and I-gel in Pediatric Airway Management for Day-Case Surgery Unde · NA · not yet recruiting
- NCT07348146 — Hand-Sewn vs. Stapled Anastomosis in SADI-S: Early Postoperative Complications. · NA · enrolling by invitation
- NCT07077265 — Comparing Two Different Norepinephrine Infusion Rates for Prophylaxis Against Spinal-induced Hypotension in Elderly · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03854812 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kasr El Aini Hospital
- Last refreshed: 13 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03854812.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing