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NCT03852654

18F-DCFPyL PET-CT Scan and Prostate Cancer

Status unknown Phase 2, PHASE3 Last updated 25 February 2019
What this trial tests

Phase 2, PHASE3 trial testing 18F-DCFPyL in Prostate Cancer Adenocarcinoma in 170 participants. Status unknown.

Timeline
22 July 2018
Primary endpoint
30 December 2019
30 June 2020

Quick facts

Lead sponsorLida Jafari
PhasePhase 2, PHASE3
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment170
Start date22 July 2018
Primary completion30 December 2019
Estimated completion30 June 2020
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Lida Jafari

Who can join

18 and older, male only, with Prostate Cancer Adenocarcinoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Primary Objective: The primary objective of this study is to assess the efficacy of 18F-DCFPyL PET-CT for initial staging of prostate cancer in Veterans compared to conventional imaging (99mTc-MDP bone scan and Diagnostic CT or MRI). The primary clinical endpoint of our study is the percent of Veterans with prostate cancer in which the 18F-DCFPyL PET-CT identifies M1 disease at initial staging. Secondary Objectives: Frequency of the change in primary treatment plan after initial staging.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The Impact of <sup>18</sup>F-DCFPyL PET-CT Imaging on Initial Staging, Radiation, and Systemic Therapy Treatment Recommendations for Veterans With Aggressive Prostate Cancer.
    Parikh NR, Tsai S, Bennett C, Lewis M, et al · · 2020 · cited 4× · PMID 33305100 · DOI 10.1016/j.adro.2020.08.014

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