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NCT03850405: CHOCO-diet
Dark Chocolate, Cholesterol and Microbiota
NA trial testing Dark Chocolate in Dyslipidemias in 40 participants. Status unknown.
1 July 2019
Quick facts
| Lead sponsor | University of Bari |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 May 2019 |
| Primary completion | 1 July 2019 |
| Estimated completion | 1 March 2020 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Dark Chocolate — full drug profile →
Conditions studied
- Dyslipidemias — all drugs for Dyslipidemias →
- Hypertriglyceridemia — all drugs for Hypertriglyceridemia →
Sponsor
University of Bari
Who can join
Adults 40 to 60, any sex, with Dyslipidemias or Hypertriglyceridemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Scientific evidence shows that a major consume of flavonoids is associated with a minor risk of coronary disease and a modification of the gut microbiome profile. Dark chocolate has a major quantity of flavonoids by weight in comparison to wine, dark tea, blueberry juice, apples and, in particular the flavanols (i.e. catechin, epicatechin and procyanidin) can have protective and metabolic effects with reduction of the insulin resistance and improvement of the endothelial function in adults. In line with the aforementioned evidence, the present study has the aim of analyze the effect of dark chocolate (70%) on cardiovascular risk and on the metabolism in a population with mild dyslipidemia.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03850405
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT03195465 — The Effect of High Antioxidant Cacao on Behaviors in Children With Autism Spectrum Disorder · NA · terminated
- NCT02764203 — ChOcolate COnsumption And Blood Pressure (COCOA-BP): A Wearable Devices Pilot Trial · NA · completed
Other recruiting trials for Dyslipidemias
Currently open trials in the same condition.
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- NCT06380322 — Military Health and Nutrition Examination Study · recruiting
- NCT06183307 — Effects of Nattokinase on Inflammation and Cardiovascular Risk Markers in Patients With Dyslipidemia · NA · recruiting
Other University of Bari trials
Trials by the same sponsor.
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- NCT07050693 — Efficacy of a 2'-Fucosylactose-based Food Supplement on the Prevention of Respiratory and Gastrointestinal Infections. · NA · recruiting
- NCT06719999 — PRIMA Project- Box for Heath and Tradition (B4HT) · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03850405 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Bari
- Last refreshed: 17 April 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03850405.
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