Last reviewed · How we verify

NCT03847571: AZ

Acetazolamide (AZ) for Management of Alkalosis in Bartter Syndrome

Status unknown Last updated 20 February 2019
What this trial tests

trial testing Acetazolamide in Bartter Syndrome in 20 participants. Status unknown.

Timeline
10 January 2019
Primary endpoint
30 October 2019
30 December 2019

Quick facts

Lead sponsorTehran University of Medical Sciences
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment20
Start date10 January 2019
Primary completion30 October 2019
Estimated completion30 December 2019
Sites4 locations across Iran

Drugs / interventions tested

Conditions studied

Sponsor

Tehran University of Medical Sciences

Who can join

Adults 1 to 10, any sex, with Bartter Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this prospective controlled cross over clinical trial, the investigators aim to evaluate the efficacy and safety of acetazolamide for the management of metabolic alkalosis in children with Bartter syndrome. Urine and blood electrolytes will be measured before and after acetazolamide treatment. The primary end point is a change in polyuria, hypokalemia, and metabolic alkalosis.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Molecular Basis, Diagnostic Challenges and Therapeutic Approaches of Bartter and Gitelman Syndromes: A Primer for Clinicians.
    Nuñez-Gonzalez L, Carrera N, Garcia-Gonzalez MA. · · 2021 · cited 27× · PMID 34768847 · DOI 10.3390/ijms222111414
  2. Advances in Diagnosis and Treatment of Inherited Kidney Diseases in Children.
    Wang G, Liao M, Tan DJ, Chen X, et al · · 2024 · cited 1× · PMID 39664340 · DOI 10.1159/000541564

Verify or expand the search:

Other trials of Acetazolamide

Trials testing the same drug.

Other recruiting trials for Bartter Syndrome

Currently open trials in the same condition.

Other Tehran University of Medical Sciences trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03847571.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing