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NCT03845634

Validation of a Non-Motor Fluctuation Assessment Instrument (NoMoFA) for Parkinson's Disease

Completed Last updated 8 July 2020
What this trial tests

trial in Parkinson Disease in 202 participants. Completed in 11 September 2019.

Timeline
13 September 2018
Primary endpoint
11 September 2019
11 September 2019

Quick facts

Lead sponsorAssistive Technology Clinic, Canada
StatusCompleted
Study typeOBSERVATIONAL
Enrollment202
Start date13 September 2018
Primary completion11 September 2019
Estimated completion11 September 2019
Sites1 location across Canada

Conditions studied

Sponsor

Assistive Technology Clinic, Canada

Who can join

Eligibility, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Investigators have developed a comprehensive questionnaire that assesses the presence of non-motor fluctuations (NMFs) in individuals with Parkinson's disease (PD). To date, 189 participants with PD have been assessed for preliminary data analysis prior to developing the penultimate version. At this time the objectives are to: (i) assess the scale's internal consistency and item-to-total correlations; (ii) assess test-retest reliability; (iii) use factor analysis and reliability measures to guide item reduction; (iv) assess construct validity; and (v) assess the scales ability to discriminate between static non-motor symptoms and non-motor symptoms which fluctuate (vi) estimate the relative distribution of cognitive, psychiatric, autonomic, sleep and sensory NMFs in PD patients with motor fluctuations and their impact on quality of life in Parkinson's disease.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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