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NCT03845257
Correlation of FeNO, Blood Eosinophils, Bronchoalveolar Lavage Findings and Bronchial Epithelium Histopathology in Patients With Chronic Obstructive Pulmonary Disease and Asthma
trial testing Blood sampling, FeNO, bronchoalveolar lavage, bronchoscopic tissue sampling in Obstructive Lung Diseases in 14 participants. Terminated before completion.
8 January 2020
Quick facts
| Lead sponsor | Heidelberg University |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 14 |
| Start date | 14 February 2019 |
| Primary completion | 8 January 2020 |
| Estimated completion | 8 January 2020 |
| Sites | 3 locations across Germany, Australia |
Drugs / interventions tested
- Blood sampling, FeNO, bronchoalveolar lavage, bronchoscopic tissue sampling
Conditions studied
- Obstructive Lung Diseases — all drugs for Obstructive Lung Diseases →
Sponsor
Heidelberg University
Who can join
18 and older, any sex, with Obstructive Lung Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Scientific research focuses on "eosinophilic inflammation" as it seems to guide the therapeutic regimen in patients with asthma and COPD. The primary objective of this prospective trial is to evaluate which parameter(s) best reflects eosinophilic inflammation by correlating tissue eosinophils (endobronchial biopsy, protected specimen brush sampling) with FeNO, peripheral blood eosinophils, and eosinophils in the bronchoalveolar lavage of patients with obstructive pulmonary disease.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03845257
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Obstructive Lung Diseases
Currently open trials in the same condition.
- NCT02073708 — A Population-based Investigation of Asthma in the Telemark Region of Norway · active not recruiting
Other Heidelberg University trials
Trials by the same sponsor.
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- NCT06018272 — Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany · NA · recruiting
- NCT06852599 — Long-term Outcomes of Implants in Patients with Periodontitis · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03845257 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Heidelberg University
- Last refreshed: 7 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03845257.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing