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NCT03843606
Modified Ketogenic Diet in Patients With McArdle Disease Part A
NA trial testing Modified ketogenic diets in McArdle Disease in 11 participants. Completed in 8 May 2019.
1 May 2019
Quick facts
| Lead sponsor | Rigshospitalet, Denmark |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 11 |
| Start date | 16 February 2019 |
| Primary completion | 1 May 2019 |
| Estimated completion | 8 May 2019 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Modified ketogenic diets
Conditions studied
- McArdle Disease — all drugs for McArdle Disease →
Sponsor
Rigshospitalet, Denmark
Who can join
Adults 18 to 80, any sex, with McArdle Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
McArdle disease, glycogen storage disease type V, is a rare metabolic disease. Affected individuals are unable to utilize sugar stored as glycogen in muscle. We hypothesize that a modified ketogenic diet could be a potential treatment option, by providing ketones as alternative fuel substrates for working muscle. In this open interventional pilot study we wish to investigate 3 different modified ketogenic diet regimes, to find an optimal composition of a modified ketogenic diet that ensures adequate degree of ketosis and at the same time is well tolerated for patients with McArdle disease.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
McArdle Disease: New Insights into Its Underlying Molecular Mechanisms.
Llavero F, Arrazola Sastre A, Luque Montoro M, Gálvez P, et al · · 2019 · cited 40× · PMID 31775340 · DOI 10.3390/ijms20235919
Verify or expand the search:
- PubMed search for NCT03843606
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for McArdle Disease
Currently open trials in the same condition.
- NCT05943678 — Novel Metabolic Muscular Biomarkers in Pompe Disease - a Non-invasive Magnetic Resonance Exploratory Pilot Study. · active not recruiting
Other Rigshospitalet, Denmark trials
Trials by the same sponsor.
- NCT07401368 — Clinicians' Trust in AI-Based Fetal Growth Estimates · NA · not yet recruiting
- NCT07442357 — The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial · NA · not yet recruiting
- NCT07528729 — Alcohol as a Modifiable Risk Factor for Atrial Fibrillation · NA · not yet recruiting
- NCT07511439 — Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission · Phase 4 · not yet recruiting
- NCT07467187 — Invasive Home Ventilation in Denmark · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03843606 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rigshospitalet, Denmark
- Last refreshed: 10 May 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03843606.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing