Last reviewed · How we verify
NCT03843242: LEADER
Evaluation of Ventricular Pacing Suppression Algorithms in Dual Chamber Pacemaker
NA trial testing Pacemaker with Fixed long AV delay in Sick Sinus Syndrome in 146 participants. Completed in 23 November 2022.
24 June 2021
Quick facts
| Lead sponsor | Keimyung University Dongsan Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 146 |
| Start date | 30 May 2019 |
| Primary completion | 24 June 2021 |
| Estimated completion | 23 November 2022 |
| Sites | 6 locations across South Korea |
Drugs / interventions tested
- Pacemaker with Fixed long AV delay
- Pacemaker with VpS® algorithm on
- Pacemaker with IRSplus algorithm on
Conditions studied
- Sick Sinus Syndrome — all drugs for Sick Sinus Syndrome →
- Pacemaker — all drugs for Pacemaker →
- Heart Failure — all drugs for Heart Failure →
Sponsor
Keimyung University Dongsan Medical Center
Who can join
20 and older, any sex, with Sick Sinus Syndrome or Pacemaker. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The recent study using IRSplus and VpS algorithm from Biotronik pacemaker showed the significant reduction in ventricular pacing to less than 3%. The purpose of this study is to evaluate the efficacy of IRSplus and VpS algorithm in reducing ventricular pacing compared with conventional DDD pacing with a fixed AV delay.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03843242
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sick Sinus Syndrome
Currently open trials in the same condition.
- NCT07360067 — Prospective Cohort Study of Bachmann Bundle Versus Right Atrial Appendage Pacing: Impact on Atrial Cardiomyopathy Evalua · recruiting
- NCT07314008 — Left Bundle Branch Versus Minimized Ventricular Pacing in Patients With Sick Sinus Syndrome and Prolonged AV Interval · NA · recruiting
- NCT06652750 — Evaluating the Safety and Effectiveness of 5G Cloud Follow-up for Cardiovascular Implantable Electronic Devices · NA · recruiting
- NCT06288633 — Cardioneuroablation for Bradyarrhythmia · NA · recruiting
Other Keimyung University Dongsan Medical Center trials
Trials by the same sponsor.
- NCT06963424 — Pain Relief and and Peripheral Perfusion Index During Erector Spinae Block · NA · completed
- NCT06471907 — Comparison of Pain Relief and Peripheral Perfusion Index · NA · recruiting
- NCT07210073 — Video Education to Improve Blood Pressure Control in Patients With Ischemic Heart Disease and Hypertension (V-EDUCATE) · NA · completed
- NCT06149299 — Great Occipital Nerve Block Using Different Approach · NA · unknown
- NCT05705362 — Simple Crossover Versus Side Branch Opening in Patients With Non-Left Main Bifurcation Lesion · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03843242 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Keimyung University Dongsan Medical Center
- Last refreshed: 31 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03843242.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing