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NCT03842254
Use of Erythropoietin to Expand Regulatory T Cells in Autoimmune Liver Disease
EARLY_PHASE1 trial testing Erythropoietin in Autoimmune Hepatitis in 6 participants. Completed in 18 February 2021.
18 February 2021
Quick facts
| Lead sponsor | Northwestern University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 6 |
| Start date | 25 January 2019 |
| Primary completion | 18 February 2021 |
| Estimated completion | 18 February 2021 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Erythropoietin — full drug profile →
Conditions studied
- Autoimmune Hepatitis — all drugs for Autoimmune Hepatitis →
Sponsor
Northwestern University
Who can join
Adults 18 to 74, any sex, with Autoimmune Hepatitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study evaluates the effect of erythropoietin on the number and function of regulatory T cells in adults with autoimmune hepatitis. Participants will receive a single dose of erythropoietin, and then the investigators will collect blood at different time points for analysis of regulatory T cell number and function.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Novel Diagnostic and Therapeutic Strategies in Juvenile Autoimmune Hepatitis.
Sciveres M, Nastasio S, Maggiore G. · · 2019 · cited 11× · PMID 31616649 · DOI 10.3389/fped.2019.00382
Verify or expand the search:
- PubMed search for NCT03842254
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Erythropoietin
Trials testing the same drug.
- NCT06983756 — " Evaluation of Erythropoietin Therapy in Patients With End-Stage Kidney Disease on Regular Hemodialysis: Hemoglobin Out · not yet recruiting
- NCT06590155 — Erythropoietin in HIE Neonate · EARLY_PHASE1 · not yet recruiting
- NCT06542393 — PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG) · Phase 2 · recruiting
- NCT05395195 — Erythropoietin for Neonatal Encephalopathy in LMIC (EMBRACE Trial) · Phase 3 · recruiting
- NCT05300477 — Pharmacological Countermeasures for High Altitude · Phase 4 · active not recruiting
Other recruiting trials for Autoimmune Hepatitis
Currently open trials in the same condition.
- NCT06381453 — Belimumab in Autoimmune Hepatitis · Phase 2 · recruiting
- NCT06455280 — A Study of SIPLIZUMAB in AILD and LT Patients · Phase 1 · recruiting
- NCT06519162 — Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome · recruiting
- NCT06250309 — Mediterranean Diet Versus Western Diet on Fatigue in Autoimmune Hepatitis Patients · NA · recruiting
- NCT06078098 — Development of a Autoimmune Hepatitis Patient's Database Linked to a Biological Sample Storage · recruiting
Other Northwestern University trials
Trials by the same sponsor.
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- NCT07392775 — ALDH2 Genetic Testing in East Asian Community · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03842254 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Northwestern University
- Last refreshed: 4 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03842254.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing