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NCT03841253
Treatment of Vision Disturbances Due to Corneal Irregularities by Trans-epithelial Optical Phototherapeutic Keratectomy (TE-oPTK)
NA trial testing Trans-epithelial PTK in Corneal Astigmatism in 45 participants. Participants enrolled and being followed up; not accepting new ones.
1 March 2028
Quick facts
| Lead sponsor | London Vision Clinic |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 45 |
| Start date | 1 August 2019 |
| Primary completion | 1 March 2028 |
| Estimated completion | 1 November 2028 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Trans-epithelial PTK
- Trans-epithelial PTK (retrospective data collection)
- EpiMaster Application Software
Conditions studied
- Corneal Astigmatism — all drugs for Corneal Astigmatism →
Sponsor
London Vision Clinic
Who can join
Adults 21 to 70, any sex, with Corneal Astigmatism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study sets out to evaluate the EpiMaster application software for use in predicting the refractive change induced by a trans-epithelial phototherapeutic keratectomy (TE-PTK) procedure in eyes with irregularly irregular astigmatism. If validation criteria are met during the observational phase, the software refractive prediction will be used to plan the refractive correction in TE-PTK treatments.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03841253
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Corneal Astigmatism
Currently open trials in the same condition.
- NCT07081919 — Effectiveness, Stability and Influence Factors of Femtosecond Laser Assisted Cataract Surgery · recruiting
- NCT04251143 — Dresden Corneal Disease and Treatment Study · recruiting
Other London Vision Clinic trials
Trials by the same sponsor.
- NCT03473847 — Repeatability, Reproducibility and Comparison of Cirrus OCT, RTVue OCT, MS-39 OCT, and Insight 100 VHFDU · NA · suspended
- NCT02519985 — Repeatability and Reproducibility of the ArcScan Insight 100 VHF Digital Ultrasound · NA · suspended
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03841253 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by London Vision Clinic
- Last refreshed: 12 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03841253.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing