NCT03837431 is a clinical trial of Skin slit in Cutaneous Leishmaniases, sponsored by Institute of Tropical Medicine, Belgium.

Who is sponsoring NCT03837431?

NCT03837431 is sponsored by Institute of Tropical Medicine, Belgium.

What drugs are being tested in NCT03837431?

Interventions in NCT03837431: Skin slit, Dental broach, Tape disc.

What condition does NCT03837431 study?

NCT03837431 studies Cutaneous Leishmaniases.

Is NCT03837431 still recruiting?

NCT03837431 is currently completed. Last updated 1 March 2023.

Last reviewed 2023-03-01 · How we verify

NCT03837431

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cutaneous Leishmaniasis Diagnostic Study

Completed Last updated 1 March 2023

What this trial tests

trial testing Skin slit in Cutaneous Leishmaniases in 351 participants. Completed in 31 January 2023.

Timeline

13 February 2019

Primary endpoint
12 August 2022

31 January 2023

Quick facts

Lead sponsor	Institute of Tropical Medicine, Belgium
Status	Completed
Study type	OBSERVATIONAL
Enrollment	351
Start date	13 February 2019
Primary completion	12 August 2022
Estimated completion	31 January 2023
Sites	1 location across Ethiopia

Drugs / interventions tested

Skin slit
Dental broach
Tape disc

Conditions studied

Cutaneous Leishmaniases — all drugs for Cutaneous Leishmaniases →

Sponsor

Institute of Tropical Medicine, Belgium

Who can join

2 and older, any sex, with Cutaneous Leishmaniases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The performance of the CL Detect Rapid test will be tested in individuals with suspected cutaneous leishmaniasis in Ethiopia using both skin slit and dental broach samples against a combined reference of microscopy and PCR. Alternative sampling methods will also be evaluated.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Evaluation of the CL Detect Rapid Test in Ethiopian patients suspected for Cutaneous Leishmaniasis.
van Henten S, Fikre H, Melkamu R, Dessie D, et al · · 2022 · cited 20× · PMID 35041672 · DOI 10.1371/journal.pntd.0010143
First report of cutaneous leishmaniasis caused by Leishmania donovani in Ethiopia.
Amare GA, Mekonnen GG, Kassa M, Addisu A, et al · · 2023 · cited 11× · PMID 38104111 · DOI 10.1186/s13071-023-06057-9
Evaluation of Less Invasive Sampling Tools for the Diagnosis of Cutaneous Leishmaniasis.
van Henten S, Kassa M, Fikre H, Melkamu R, et al · · 2024 · cited 7× · PMID 38560600 · DOI 10.1093/ofid/ofae113
Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis.
Churiso G, van Henten S, Cnops L, Pollmann J, et al · · 2020 · cited 7× · PMID 32939358 · DOI 10.1093/ofid/ofaa364
Evaluation of Loopamp Leishmania detection kit for the diagnosis of cutaneous leishmaniasis in Ethiopia.
Taye B, Melkamu R, Tajebe F, Ibarra-Meneses AV, et al · · 2024 · cited 4× · PMID 39407317 · DOI 10.1186/s13071-024-06475-3

Verify or expand the search:

Other recruiting trials for Cutaneous Leishmaniases

Currently open trials in the same condition.

NCT06514560 — OPTImizing MIltefosine Treatment for Cutaneous LEISHmaniasis Patients · recruiting

Other Institute of Tropical Medicine, Belgium trials

Trials by the same sponsor.

NCT07463040 — Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) · Phase 3 · not yet recruiting
NCT07174648 — Testing of a New Rapid Antigen Test for Plague in Ituri, Democratic Republic of the Congo. · not yet recruiting
NCT07499739 — Mpox Biology, Outcome, Transmission and Epidemiology - Tracking the Immune Response After mpoX vaCcination (MBOTE-TRAXX) · Phase 4 · not yet recruiting
NCT07342829 — Prospective Follow-up After MVA-BN Booster Vaccination · not yet recruiting
NCT06839989 — An Immunogenicity and Safety Trial of MVA-BN in Adults Living With HIV for the Prevention of Mpox Infection, in Kinshasa · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03837431 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Institute of Tropical Medicine, Belgium
Last refreshed: 1 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03837431.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing