NCT03837223 is a clinical trial of GnRH agonist in GnRH Trigger and Rescue Protocol, sponsored by Istituto Clinico Humanitas.

Who is sponsoring NCT03837223?

NCT03837223 is sponsored by Istituto Clinico Humanitas.

What drugs are being tested in NCT03837223?

Interventions in NCT03837223: GnRH agonist.

What condition does NCT03837223 study?

NCT03837223 studies GnRH Trigger and Rescue Protocol.

Is NCT03837223 still recruiting?

NCT03837223 is currently completed. Last updated 12 February 2019.

Last reviewed 2019-02-12 · How we verify

NCT03837223

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RESCUE PROTOCOL AND FRESH EMBRYO TRANSFER

Completed Last updated 12 February 2019

What this trial tests

trial testing GnRH agonist in GnRH Trigger and Rescue Protocol in 271 participants. Completed in 31 December 2016.

Timeline

1 March 2013

Primary endpoint
31 December 2016

31 December 2016

Quick facts

Lead sponsor	Istituto Clinico Humanitas
Status	Completed
Study type	OBSERVATIONAL
Enrollment	271
Start date	1 March 2013
Primary completion	31 December 2016
Estimated completion	31 December 2016

Drugs / interventions tested

GnRH agonist — full drug profile →

Conditions studied

GnRH Trigger and Rescue Protocol — all drugs for GnRH Trigger and Rescue Protocol →

Sponsor

Istituto Clinico Humanitas

Who can join

Adults 18 to 38, female only, with GnRH Trigger and Rescue Protocol. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ovarian Hyperstimulation Syndrome (OHSS) is one of the most dangerous complications of Assisted Reproductive Technologies (ART) cycles. The use in clinical practice of the GnRH antagonist has made it possible to perform the trigger with GnRH analogues reducing the risk of OHSS. The trigger with analogue increases the Abortion Rate (AR) and reduces the Ongoing Pregnancy Rate (OPR), because the luteal phase in these cycles is particularly deficient. To reduce this occurrence several studies have focused on the importance of support of the luteal phase. The aims of study is to evaluate OPR and AR in patients at intermediate risk of OHSS (\<18 recovered oocytes) which performed GnRH trigger and rescue protocol.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of GnRH agonist

Trials testing the same drug.

NCT07269392 — Dual Trigger With HCG and GnRH Agonist on Thawed Modified Natural Cycle Embryo Transfer · Phase 4 · not yet recruiting
NCT05838105 — Two Different Types of Luteal Phase Support in Natural Cycle Frozen Embryo Transfer and Its Effect on Pregnancy Rates · NA · unknown
NCT04356664 — Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis · Phase 2, PHASE3 · recruiting
NCT05484193 — GnRH Agonist for Luteal Phase Support. · NA · unknown
NCT04182594 — Cardiovascular Events in GnRH Agonist vs. Antagonist · Phase 2 · unknown

Other Istituto Clinico Humanitas trials

Trials by the same sponsor.

NCT06944288 — Microbiota as Early Diagnostic and predictivE Factor for Osteoarthritic Degeneration and Microbial Contamination · NA · not yet recruiting
NCT07358247 — Postoperative Outcomes of Single-stapled Anastomosis Combined With Transanal Natural Orifice Specimen Extraction · not yet recruiting
NCT07362342 — RIght VEntricle Response to Major Lung Resection in VATS and Robotic Surgery · not yet recruiting
NCT07346274 — Intra-operative Hypotension and Post-operative Lactate Level After Pancreatic-duodenectomy. · enrolling by invitation
NCT07491419 — The Impact of Fast Antimicrobial Sensitivity Testing Tools on Stewardship Antibiotic and Clinical Outcome (ACT-FAST) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03837223 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istituto Clinico Humanitas
Last refreshed: 12 February 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03837223.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing