Who is sponsoring NCT03831542?

NCT03831542 is sponsored by Centrum Clinic IVF Center.

What drugs are being tested in NCT03831542?

Interventions in NCT03831542: direct follicular aspiration, follicular flushing.

What condition does NCT03831542 study?

NCT03831542 studies Invitro Fertilization, Diminished Ovarian Reserve, Oocyte.

Is NCT03831542 still recruiting?

NCT03831542 is currently completed. Last updated 7 May 2019.

Last reviewed 2019-05-07 · How we verify

NCT03831542

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Follicular Flushing in Patients With Mono-follicular Growth Undergoing In Vitro Fertilization

Completed Last updated 7 May 2019

What this trial tests

trial testing direct follicular aspiration in Invitro Fertilization in 71 participants. Completed in 6 May 2019.

Timeline

19 February 2019

Primary endpoint
5 May 2019

6 May 2019

Quick facts

Lead sponsor	Centrum Clinic IVF Center
Status	Completed
Study type	OBSERVATIONAL
Enrollment	71
Start date	19 February 2019
Primary completion	5 May 2019
Estimated completion	6 May 2019
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

direct follicular aspiration
follicular flushing

Conditions studied

Invitro Fertilization — all drugs for Invitro Fertilization →
Diminished Ovarian Reserve — all drugs for Diminished Ovarian Reserve →
Oocyte — all drugs for Oocyte →

Sponsor

Centrum Clinic IVF Center

Who can join

Adults 18 to 40, female only, with Invitro Fertilization or Diminished Ovarian Reserve. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Retrieval of an oocyte from a follicle relies on the release of the cumulus-oocyte-complex (COC) from the follicular wall into the lumen, thereby allowing aspiration by a needle. Flushing the follicle with multiple aspirations from the same follicle is used as a means to increase the ratio of COC per aspirated follicle. Data showed that follicular flushing is not superior to direct aspiration either in normally responding patients or in poor responders undergoing in vitro fertilization (IVF). There is no data in the literature regarding the issue in patients with mono-follicular growth. Direct aspiration or repeatedly flushing the follicle for those with a single follicle will be investigated.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other Centrum Clinic IVF Center trials

Trials by the same sponsor.

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NCT03948022 — Luteal Support in Frozen-Thawed Embryo Transfer Cycles · Phase 4 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03831542 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centrum Clinic IVF Center
Last refreshed: 7 May 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03831542.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing