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NCT03830684

A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase Ⅱa Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy Adult With Influenza Fever

Status unknown Phase 2 Last updated 5 February 2019
What this trial tests

Phase 2 trial testing Baicalein Tablets 400mg in Influenza in 180 participants. Status unknown.

Timeline
1 February 2019
Primary endpoint
31 May 2019
31 October 2019

Quick facts

Lead sponsorCSPC ZhongQi Pharmaceutical Technology Co., Ltd.
PhasePhase 2
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposetreatment
Enrollment180
Start date1 February 2019
Primary completion31 May 2019
Estimated completion31 October 2019

Drugs / interventions tested

Conditions studied

Sponsor

CSPC ZhongQi Pharmaceutical Technology Co., Ltd. — full company profile →

Who can join

Adults 18 to 65, any sex, with Influenza. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study in order to evaluate the Baicalein Tablets' safety and efficiency for audit with influenza

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Targeting ferroptosis opens new avenues for the development of novel therapeutics.
    Sun S, Shen J, Jiang J, Wang F, et al · · 2023 · cited 380× · PMID 37735472 · DOI 10.1038/s41392-023-01606-1
  2. Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients.
    Su HX, Yao S, Zhao WF, Li MJ, et al · · 2020 · cited 343× · PMID 32737471 · DOI 10.1038/s41401-020-0483-6
  3. Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities.
    Cannalire R, Cerchia C, Beccari AR, Di Leva FS, et al · · 2022 · cited 171× · PMID 33186044 · DOI 10.1021/acs.jmedchem.0c01140
  4. Ferroptosis: mechanisms and therapeutic targets.
    Zhou Q, Meng Y, Le J, Sun Y, et al · · 2024 · cited 32× · PMID 39568772 · DOI 10.1002/mco2.70010
  5. Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells.
    Khan MA, Nag P, Grivei A, Giuliani KTK, et al · · 2022 · cited 31× · PMID 35110539 · DOI 10.1038/s41419-022-04527-z
  6. Update on histone deacetylase inhibitors in peripheral T-cell lymphoma (PTCL).
    Lu G, Jin S, Lin S, Gong Y, et al · · 2023 · cited 25× · PMID 37533111 · DOI 10.1186/s13148-023-01531-8
  7. Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury.
    Wang X, Kim CS, Adams BC, Wilkinson R, et al · · 2024 · cited 23× · PMID 38244399 · DOI 10.1016/j.redox.2024.103042
  8. Possible Therapeutic Use of Natural Compounds Against COVID-19.
    Khan N, Chen X, Geiger JD. · · 2021 · cited 23× · PMID 33768214 · DOI 10.33696/signaling.2.036

Verify or expand the search:

Other recruiting trials for Influenza

Currently open trials in the same condition.

Other CSPC ZhongQi Pharmaceutical Technology Co., Ltd. trials

Trials by the same sponsor.

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Data sources for this page

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