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NCT03826914

The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults

Completed NA Results posted Last updated 29 October 2020
What this trial tests

NA trial testing CardioFlex Q10 in Cardiovascular Diseases in 69 participants. Completed in 1 August 2020.

Timeline
6 November 2018
Primary endpoint
1 June 2019
1 August 2020

Quick facts

Lead sponsorUniversity of Manitoba
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposeprevention
Enrollment69
Start date6 November 2018
Primary completion1 June 2019
Estimated completion1 August 2020
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

University of Manitoba

Who can join

Adults 30 to 65, any sex, with Cardiovascular Diseases or Cardiovascular Abnormalities. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Change From Baseline of Total Cholesterol After 90 Days Primary · Baseline and 90 days

Total cholesterol is the total amount of cholesterol in the blood. Change = Day 90 score - baseline score.

GroupValue95% CI
Cardioflex Group-0.57± 1.06
Placebo Group-1.09± 1.05
Heart Rate Variability Secondary · Baseline and day 90

Heart rate variability is a measure of the variation in time between each heartbeat. Change = day 90 score - baseline score

GroupValue95% CI
Cardioflex3.49± 10.86
Placebo-6.27± 10.55

Sponsor's own description

Cardiovascular diseases (CVD), primarily heart disease and stroke, are the leading causes of death and prescription drug use in Canada. Research on certain dietary supplements looks promising as a way to help reduce CVD risk factors. Studies show that supplementation of certain nutrients such as antioxidants, amino acids, electrolytes, vitamins and minerals may effectively reduce cardiovascular risk factors. The dietary supplement CardioFlex Q10, which is high in the aforementioned components, was developed to help regulate the body's production of cholesterol, strengthen the arteries and heart, and reverse oxidation. The overall objective of this study is to determine if 90 days of supplementing with CardioFlex Q10 can reduce CVD risk factors in adults, independent of other dietary or physical activity changes.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Iron homeostasis and ferroptosis in muscle diseases and disorders: mechanisms and therapeutic prospects.
    Ru Q, Li Y, Zhang X, Chen L, et al · · 2025 · cited 14× · PMID 40000618 · DOI 10.1038/s41413-024-00398-6

Verify or expand the search:

Other recruiting trials for Cardiovascular Diseases

Currently open trials in the same condition.

Other University of Manitoba trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03826914.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing